LY6E antibody (AA 41-70)

Catalog No. ABIN657739

Product Details anti-LY6E Antibody

Target: LY6E (Lymphocyte Antigen 6 Complex, Locus E (LY6E))

Binding Specificity: AA 41-70

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LY6E antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LY6E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 amino acids from the Central region of human LY6E.

Clone: RB32741

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: LY6E Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for LY6E

Target: LY6E (Lymphocyte Antigen 6 Complex, Locus E (LY6E))

Alternative Name: LY6E (LY6E Products)

Synonyms: LY6E antibody, RIG-E antibody, RIGE antibody, SCA-2 antibody, SCA2 antibody, TSA-1 antibody, 9804 antibody, Ly67 antibody, Sca-2 antibody, Tsa1 antibody, lymphocyte antigen 6 family member E antibody, lymphocyte antigen 6 complex, locus E antibody, LY6E antibody, Ly6e antibody

Background: Sca1, also known as Ly6A/E, is a member of the Ly6 multigene family of type V glycophosphatidylinositol anchored cell surface proteins. It is expressed on multipotent hematopoietic stem cells in bone marrow of mice with both the Ly6.1 and Ly6.2 allotypes. In the periphery, Sca1 exhibits a pattern of expression which is based on differences between the two allotypes. Ly6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have few Sca1+ resting peripheral lymphocytes, whereas Ly6.2 strains (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have relatively high numbers of Sca1+ lymphocytes. The expression of Sca1 is dramatically upregulated in all strains upon cellular activation.

Molecular Weight: 13507

Gene ID: 4061

NCBI Accession: NP_001120685, NP_002337

UniProt: Q16553

Pathways: Hormone Transport