Lymphocyte Antigen 6 Complex, Locus E (LY6E) (AA 41-70), (Center) antibody

Details for Product No. ABIN657739
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Antigen
Epitope
AA 41-70, Center
(21), (15), (2), (1), (1), (1)
Reactivity
Human
(31), (13)
Host
Rabbit
(31), (13)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(3), (3), (3), (3), (3), (3)
Application
Western Blotting (WB)
(34), (21), (9), (8), (3), (2), (1)
Pubmed 1 reference available
Quantity 400 μL
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Immunogen This LY6E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-70 AA from the Central region of human LY6E.
Clone RB32741
Isotype Ig
Specificity This LY6E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-71 amino acids from the Central region of human LY6E.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name LY6E (LY6E Antibody Abstract)
Background Sca1, also known as Ly6A/E, is a member of the Ly6 multigene family of type V glycophosphatidylinositol anchored cell surface proteins. It is expressed on multipotent hematopoietic stem cells in bone marrow of mice with both the Ly6.1 and Ly6.2 allotypes. In the periphery, Sca1 exhibits a pattern of expression which is based on differences between the two allotypes. Ly6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have few Sca1+ resting peripheral lymphocytes, whereas Ly6.2 strains (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have relatively high numbers of Sca1+ lymphocytes. The expression of Sca1 is dramatically upregulated in all strains upon cellular activation.
Synonyms: Lymphocyte antigen 6E,LY6E,9804, RIGE, SCA2, TSA1
Molecular Weight 13507 DA
Gene ID 4061
NCBI Accession NP_002337, NP_001120685
UniProt Q16553
Research Area Cell Signaling, Cell Structure, Protein Modifications
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.48 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment LY6E Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Lymphocyte Antigen 6 Complex, Locus E (LY6E) (AA 41-70), (Center) antibody LY6E Antibody (Center) (ABIN657739) western blot analysis in MCF-7 cell line lysates ...
Background publications Davila, Froeling, Tan et al.: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).

Validation Images
Catalog No. ABIN657739
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