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CENPA antibody (Centromere Protein A) (AA 82-110)

Details for Product anti-CENPA Antibody No. ABIN657764, Supplier: Login to see
Antigen
  • BcDNA:RE21270
  • CENP-A
  • CENP-A/CID
  • CENP-A/Cid
  • CENP-C
  • CENPA
  • CG13329
  • CID
  • CID/CENP-A
  • CenH3
  • CenH3/CID
  • CenH3[CID]
  • CenH3[Cid]
  • Cenp-A
  • CenpA
  • CenpA/CID
  • Cid
  • Cid[Mel]
  • Dmel\\CG13329
  • cenH3
  • cenpA
  • cenpx
  • cenp-a
  • sim2
  • Cenp-a
  • RGD1563607
Epitope
AA 82-110, Center
22
15
14
12
9
5
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
128
7
5
2
1
1
1
Host
Rabbit
79
45
5
Clonality (Clone)
Polyclonal ()
Conjugate
This CENPA antibody is un-conjugated
5
5
4
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
91
44
25
16
13
12
7
3
2
1
1
1
Supplier
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Immunogen This CENPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-110 AA from the Central region of human CENPA.
Clone RB33757
Isotype Ig
Specificity This CENPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-110 amino acids from the Central region of human CENPA.
Predicted Reactivity Cow (Bovine),Hamster
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name CENPA (CENPA Antibody Abstract)
Background Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq].
Synonyms: Histone H3-like centromeric protein A,CENPA,
Molecular Weight 15991 DA
Gene ID 1058
NCBI Accession NP_001800, NP_001035891
UniProt P49450
Research Area Ubiquitin-related antibodies, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Chromatin, Signaling, Cell Structure
Pathways
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.42 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment CENPA Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-CENPA antibody (Centromere Protein A) (AA 82-110) (ABIN657764) CENPA Antibody (Center) (ABIN657764) western blot analysis in Jurkat cell line lysate...
Background publications Sekulic, Bassett, Rogers et al.: "The structure of (CENP-A-H4)(2) reveals physical features that mark centromeres." in: Nature, Vol. 467, Issue 7313, pp. 347-51, 2010 (PubMed).

Carroll, Milks, Straight: "Dual recognition of CENP-A nucleosomes is required for centromere assembly." in: The Journal of cell biology, Vol. 189, Issue 7, pp. 1143-55, 2010 (PubMed).