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Details for Product No. ABIN657764

Centromere Protein A (CENPA) (AA 82-110), (Center) antibody

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Antigen
Synonyms
CENP-A, CenH3, Cenp-A, RGD1563607, BcDNA:RE21270, CENP-A/CID, CENP-A/Cid, CENP-C, CENPA, CG13329, CID, CID/CENP-A, CenH3/CID, CenH3[CID], CenH3[Cid], CenpA, CenpA/CID, Cid, Cid[Mel], Dmel\\CG13329, ce ... show more
Epitope
»Alternatives AA 82-110, Center
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN657764
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This CENPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-110 AA from the Central region of human CENPA.
Clone RB33757
Isotype Ig
Specificity This CENPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-110 amino acids from the Central region of human CENPA.
Predicted Reactivity Cow (Bovine),Hamster
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name CENPA
Background Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq].
Synonyms: Histone H3-like centromeric protein A,CENPA,
Molecular Weight 15991 DA
Gene ID 1058
UniProt NP_001800.1, P49450, NP_001035891.1
Research Area Ubiquitin-related antibodies, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Chromatin, Signaling, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.42 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment CENPA Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Background publications Carroll, Milks, Straight: "Dual recognition of CENP-A nucleosomes is required for centromere assembly." in: The Journal of cell biology, Vol. 189, Issue 7, pp. 1143-55, 2010 (PubMed).

Sekulic, Bassett, Rogers et al.: "The structure of (CENP-A-H4)(2) reveals physical features that mark centromeres." in: Nature, Vol. 467, Issue 7313, pp. 347-51, 2010 (PubMed).

Alternatives for antigen "Centromere Protein A (CENPA)", type "Antibodies"
Hosts (57), (11), (3)
Reactivities (66), (14), (14), (13), (12), (12), (2), (1)
Applications (40), (29), (20), (14), (14), (7), (5), (4), (2), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (18), (14), (3), (3), (3), (2), (2), (1), (1), (1), (1)
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