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D-Amino-Acid Oxidase (DAO) (AA 259-287), (Center) antibody

Details for Product No. ABIN657862
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Antigen
Synonyms daao, oxda, damox, dao, DAO, DKFZp469N2232, zgc:77858, zgc:76928, SC5F2A.23c, wu:fb55b11, zgc:113922, MGC114783, Abp, Abp1, 1600012D06Rik, DAAO, DAMOX, AI987963, Dao-1, Dao1, OXDA
Epitope
AA 259-287, Center
(6), (4), (2), (2), (2), (1), (1)
Reactivity
Human
(22), (19), (5), (4), (1), (1)
Host
Rabbit
(20), (9), (9), (4)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(6), (2), (1), (1), (1), (1)
Application
Western Blotting (WB)
(38), (31), (9), (6), (4), (2), (2), (2), (2), (2)
Pubmed 1 reference available
Quantity 400 µL
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Catalog No. ABIN657862
291.50 $
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Immunogen This DAO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 AA from the Central region of human DAO.
Clone RB21621
Isotype Ig
Specificity This DAO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-287 amino acids from the Central region of human DAO.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name DAO
Background This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known, it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia.
Synonyms: D-amino-acid oxidase,1610,DAMOX
Molecular Weight 39474 DA
Gene ID 1610
UniProt NP_001908.3, P14920
Research Area Metabolism, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment DAO Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-D-Amino-Acid Oxidase (DAO) (AA 259-287), (Center) antibody DAO Antibody (Center) (ABIN657862) western blot analysis in Jurkat cell line lysates (35 µg/lane). This demonstrates the DAO antibody detected the DAO protein (arrow).
Background publications Mitchell, Paul, Chen et al.: "Familial amyotrophic lateral sclerosis is associated with a mutation in D-amino acid oxidase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 16, pp. 7556-61, 2010 (PubMed).

Validation Images
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