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Details for Product No. ABIN657862

D-Amino-Acid Oxidase (DAO) (AA 259-287), (Center) antibody

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Synonyms DAAO, DAMOX, OXDA, DAO, 1600012D06Rik, Abp1, Abp, Dao, daao, oxda, damox, dao, DKFZp469N2232, zgc:77858, zgc:76928, SC5F2A.23c, wu:fb55b11, zgc:113922, MGC114783
»Alternatives AA 259-287, Center
»Alternatives Human
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
»Alternatives Un-conjugated
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN657862
Quantity 400 µL
291.50 $   Plus shipping costs $45.00
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Immunogen This DAO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 AA from the Central region of human DAO.
Clone RB21621
Isotype Ig
Specificity This DAO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-287 amino acids from the Central region of human DAO.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name DAO
Background This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known, it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia.
Synonyms: D-amino-acid oxidase,1610,DAMOX
Molecular Weight 39474 DA
Gene ID 1610
UniProt NP_001908.3, P14920
Research Area Metabolism, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment DAO Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Background publications Mitchell, Paul, Chen et al.: "Familial amyotrophic lateral sclerosis is associated with a mutation in D-amino acid oxidase." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 16, pp. 7556-61, 2010 (PubMed).

Alternatives for antigen "D-Amino-Acid Oxidase (DAO)", type "Antibodies"
Hosts (18), (14), (10), (4)
Reactivities (30), (14), (4), (3), (1), (1)
Applications (43), (34), (13), (7), (5), (2), (2), (2), (2), (2)
Conjugates (8), (4)
Epitopes (5), (3), (2), (2), (1), (1)