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Details for Product No. ABIN657926

Chymotrypsin-Like Elastase Family, Member 2A (CELA2A) (C-Term), (AA 231-260) antibody

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Antigen
Synonyms ELANE, ELA2, Ela2, Ela-2, Ela2a, ELAII, Elaii1, PE-1, ELA2A, ela2, ela2a
Epitope
»Alternatives C-Term, AA 231-260
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN657926
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This CELA2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-260 AA from the C-terminal region of human CELA2A.
Clone RB33880
Isotype Ig
Specificity This CELA2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-260 amino acids from the C-terminal region of human CELA2A.
Predicted Reactivity Pig (Porcine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name CELA2A
Background Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Like most of the human elastases, elastase 2A is secreted from the pancreas as a zymogen. In other species, elastase 2A has been shown to preferentially cleave proteins after leucine, methionine, and phenylalanine residues.
Synonyms: Chymotrypsin-like elastase family member 2A,63036,ELA2A
Molecular Weight 28888 DA
Gene ID 63036
UniProt NP_254275.1, P08217
Research Area Cell Signaling, Protein Modifications, Metabolism, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment CELA2A Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Background publications Lausen, Liu, Fliegauf et al.: "ELA2 is regulated by hematopoietic transcription factors, but not repressed by AML1-ETO." in: Oncogene, Vol. 25, Issue 9, pp. 1349-57, 2006 (PubMed).

Lamesch, Li, Milstein et al.: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, 2007 (PubMed).

Alternatives for antigen "Chymotrypsin-Like Elastase Family, Member 2A (CELA2A)", type "Antibodies"
Hosts (4), (1), (1)
Reactivities (7), (1), (1), (1), (1), (1), (1)
Applications (5), (2), (1), (1), (1)
Epitopes (3), (1), (1)
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