Barrier To Autointegration Factor 1 (BANF1) (AA 37-65), (Center) antibody

Details for Product No. ABIN657992
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Synonyms BAF, BCRP1, D14S1460, NGPS, Baf, Bcrp1, L2bp1, L2bp1/Baf, C78287, CG7380, Dmel\\CG7380, anon-WO0172774.178, dBAF, BANF1, DKFZp468C097, baf, bcrp1, fa01c01, wu:fa01c01, zgc:77767
AA 37-65, Center
(13), (8), (5), (4), (1), (1), (1)
(59), (35), (23), (12), (12)
(45), (14)
Clonality (Clone)
Polyclonal ()
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Western Blotting (WB), Immunohistochemistry (IHC)
(47), (32), (26), (19), (10), (4), (2), (2), (1)
Pubmed 3 references available
Catalog no. ABIN657992
Quantity 400 µL
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Immunogen This BANF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 AA from the Central region of human BANF1.
Clone RB34595
Isotype Ig
Specificity This BANF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-65 amino acids from the Central region of human BANF1.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name BANF1
Background The protein encoded by this gene was first identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The protein forms a homodimer which localizes to both the nucleus and cytoplasm and is specifically associated with chromosomes during mitosis. This protein binds to double stranded DNA in a non-specific manner and also binds to LEM-domain containing proteins of the nuclear envelope. This protein is thought to facilitate nuclear reassembly by binding with both DNA and inner nuclear membrane proteins and thereby recruit chromatin to the nuclear periphery. Alternative splicing results in multiple transcript variants encoding the same protein.
Synonyms: Barrier-to-autointegration factor,8815,BAF, BCRG1
Molecular Weight 10059 DA
Gene ID 8815
UniProt NP_001137457.1, NP_003851.1, O75531
Research Area Phospho-specific antibodies, Protein Modifications, Transcription Factors, Chromatin, Signaling, Cell Structure
Application Notes WB = 1:1000, IHC = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment BANF1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Barrier To Autointegration Factor 1 (BANF1) (AA 37-65), (Center) antibody BANF1 Antibody (Center) (ABIN657992) western blot analysis in Jurkat cell line lysates (35 µg/lane). This demonstrates the BANF1 antibody detected the BANF1 protein (arrow).
Background publications Haraguchi, Koujin, Osakada et al.: "Nuclear localization of barrier-to-autointegration factor is correlated with progression of S phase in human cells." in: Journal of cell science, Vol. 120, Issue Pt 12, pp. 1967-77, 2007 (PubMed).

Haraguchi, Kojidani, Koujin et al.: "Live cell imaging and electron microscopy reveal dynamic processes of BAF-directed nuclear envelope assembly." in: Journal of cell science, Vol. 121, Issue Pt 15, pp. 2540-54, 2008 (PubMed).

Montes de Oca, Shoemaker, Gucek et al.: "Barrier-to-autointegration factor proteome reveals chromatin-regulatory partners." in: PLoS ONE, Vol. 4, Issue 9, pp. e7050, 2009 (PubMed).

Hosts (45), (14)
Reactivities (59), (35), (23), (12), (12)
Applications (47), (32), (26), (19), (10), (4), (2), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (13), (8), (5), (4), (1), (1), (1)
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