Bone Morphogenetic Protein 4 (BMP4) antibody

Details for Product No. ABIN659071
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Antigen
Synonyms ZYME, BMP2B, OFC11, BMP2B1, MCOPS6, Bmp-4, Bmp2b, Bmp2b1, Bmp2b-1, BOMPR4A, bmp-4, zbmp-4, zgc:100779, BMP-4, XBMP-4, bmp2b, bmp2b1, bmp4, ofc11, xbmp4, zyme, BMP4
Reactivity
Human
(101), (38), (33), (11), (10), (8), (6), (6), (5), (2), (2), (1)
Host
Mouse
(107), (37), (7), (1)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(13), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(120), (77), (54), (32), (31), (13), (12), (10), (6), (4), (2), (1), (1), (1), (1), (1)
Pubmed 4 references available
Catalog no. ABIN659071
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This BMP4 monoclonal antibody is generated from mouse immunized with BMP4 recombinant protein.
Clone 192CT7-2-6
Isotype IgM, kappa
Specificity This BMP4 monoclonal antibody is generated from mouse immunized with BMP4 recombinant protein.
Purification This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
Alternative Name BMP4
Background The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
Synonyms: Bone morphogenetic protein 4,BMP4,BMP2B, DVR4
Molecular Weight 46555 DA
Gene ID 652
UniProt NP_570911.2, NP_001193.2, P12644, NP_570912.2
Research Area Cell Signaling, Protein Modifications, Cell Cycle, Cell Structure
Application Notes WB = 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1.2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Bone Morphogenetic Protein 4 (BMP4) antibody BMP4 Antibody western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the BMP4 antibody detected the BMP4 protein (arrow).
Background publications Jugessur, Shi, Gjessing et al.: "Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia." in: PLoS ONE, Vol. 5, Issue 7, pp. e11493, 2010 (PubMed).

Kupfer, Anderson, Hooker et al.: "Genetic heterogeneity in colorectal cancer associations between African and European americans." in: Gastroenterology, Vol. 139, Issue 5, pp. 1677-85, 1685.e1-8, 2010 (PubMed).

Kim, Lee, Jung et al.: "Genetic variants that affect length/height in infancy/early childhood in Vietnamese-Korean families." in: Journal of human genetics, Vol. 55, Issue 10, pp. 681-90, 2010 (PubMed).

Nikopensius, Jagomägi, Krjutskov et al.: "Genetic variants in COL2A1, COL11A2, and IRF6 contribute risk to nonsyndromic cleft palate." in: Birth defects research. Part A, Clinical and molecular teratology, Vol. 88, Issue 9, pp. 748-56, 2010 (PubMed).

Hosts (107), (37), (7), (1)
Reactivities (101), (38), (33), (11), (10), (8), (6), (6), (5), (2), (2), (1)
Applications (120), (77), (54), (32), (31), (13), (12), (10), (6), (4), (2), (1), (1), (1), (1), (1)
Conjugates (13), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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