BPV-1 E2 Tag antibody

Details for Product No. ABIN781761
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Antigen
Reactivity
Bovine Papillomavirus (BPV), Cow (Bovine)
(1), (1)
Host
Mouse
(1)
Clonality (Clone)
Monoclonal ()
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
(1), (1), (1), (1)
Pubmed 1 reference available
Quantity 0.1 mg
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Catalog No. ABIN781761
467.50 $
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Immunogen Recombinant full length BPV type 1 E2 protein purified from E. coli
Clone 5E11
Isotype IgG1
Specificity This antibody detects Bovine Papillomavirus E2-protein mapped to aa 199-208 (E2Tag, SSTSSDFRDR). Isolates E2 Tag-tagged proteins and associated proteins/protein binding partners by Immunoprecipitation.
Purification Affinity Chromatography on Protein A
Background The bovine papilloma virus E2 protein is the master regulator of papillomavirus replication and transcription. Binds to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory region. Can either activate or repress transcription depending on E2RE's position with regards to proximal promoter elements. Repression occurs by sterically hindering the assembly of the transcription initiation complex. The E1-E2 complex binds to the origin of DNA replication.
Alternate names: BPV1, Bovine Papilloma Virus Protein E2
Gene ID 10559
UniProt P03122
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS with 50% Glycerol
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Upon receipt, store (in aliquots) at -20°C to -70 °C.
Expiry Date 12 months
Supplier Images
anti-BPV-1 E2 Tag antibody anti-BPV-1 E2 Tag antibody
Background publications Koljak, Järving, Kurg et al.: "The basis of prostaglandin synthesis in coral: molecular cloning and expression of a cyclooxygenase from the Arctic soft coral Gersemia fruticosa." in: The Journal of biological chemistry, Vol. 276, Issue 10, pp. 7033-40, 2001 (PubMed).

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