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TMEM59 antibody (N-Term)

TMEM59 Reactivity: Human WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN783793
  • Target See all TMEM59 Antibodies
    TMEM59 (Transmembrane Protein 59 (TMEM59))
    Binding Specificity
    • 15
    • 5
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 15
    • 9
    Human
    Host
    • 24
    Rabbit
    Clonality
    • 24
    Polyclonal
    Conjugate
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TMEM59 antibody is un-conjugated
    Application
    • 20
    • 13
    • 13
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects TMEM59 at N-term.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    16 amino acid peptide near amino terminus of human TMEM59
    Top Product
    Discover our top product TMEM59 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Target
    TMEM59 (Transmembrane Protein 59 (TMEM59))
    Alternative Name
    TMEM59 (TMEM59 Products)
    Background
    Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59, a Golgi-localized protein, modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. It inhibits APP transport and shedding.Synonyms: C1orf8, HSPC001, Liver membrane-bound protein, Transmembrane protein 59
    Gene ID
    9528
    NCBI Accession
    NP_004863
    UniProt
    Q9BXS4
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