TIMP2 antibody (Middle Region)

Catalog No. ABIN929153

Product Details anti-TIMP2 Antibody

Target: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIMP2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: TIMP2 antibody was raised in rabbit using the middle region of TIMP2 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

TIMP2 Blocking Peptide, catalog no. 33R-4204, is also available for use as a blocking control in assays to test for specificity of this TIMP2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for TIMP2

Target: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Alternative Name: TIMP2 (TIMP2 Products)

Background: This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. Synonyms: Polyclonal TIMP2 antibody, Anti-TIMP2 antibody, TIMP metallopeptidase inhibitor 2 antibody, CSC-21K antibody.

Pathways: cAMP Metabolic Process