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rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5) (AA 1502-1530), (C-Term) antibody

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Synonyms ARHGEF5, GEF5, P60, TIM, TIM1, 2210412D05Rik, AA717842, AW495314, Tim1
C-Term, AA 1502-1530
(18), (17), (15), (5), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
(74), (18), (16)
(51), (17), (6), (2)
(4), (3), (3), (3), (3), (3)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(66), (46), (10), (7), (4), (3), (2), (1)
Pubmed 3 references available
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Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 1502-1530 amino acids from the C-terminal region of human ARHGEF5
Isotype Ig
Specificity This antibody reacts to ARHGEF5.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name ARHGEF5 / TIM (ARHGEF5 Antibody Abstract)
Background Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization.Synonyms: Guanine nucleotide regulatory protein TIM, Oncogene TIM, Rho guanine nucleotide exchange factor 5, Transforming immortalized mammary oncogene, p60 TIM
Gene ID 7984
NCBI Accession NP_005426
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5) (AA 1502-1530), (C-Term) antibody (ABIN950496) ARHGEF5 Antibody (C-term) western blot analysis in A2058 cell line lysates (35µg/lane...
Background publications Wang, Kumamoto, Wang et al.: "Regulation of immature dendritic cell migration by RhoA guanine nucleotide exchange factor Arhgef5." in: The Journal of biological chemistry, Vol. 284, Issue 42, pp. 28599-606, 2009 (PubMed).

Lin, Chang, Yeh et al.: "Disturbance of circadian gene expression in hepatocellular carcinoma." in: Molecular carcinogenesis, Vol. 47, Issue 12, pp. 925-33, 2008 (PubMed).

Zhang, Wolf-Yadlin, Ross et al.: "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules." in: Molecular & cellular proteomics : MCP, Vol. 4, Issue 9, pp. 1240-50, 2005 (PubMed).

Catalog No. ABIN950496
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