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rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5) (AA 1502-1530), (C-Term) antibody

Details for Product No. ABIN950496, Supplier: Log in to see
Antigen
  • ARHGEF5
  • GEF5
  • P60
  • TIM
  • TIM1
  • 2210412D05Rik
  • AA717842
  • AW495314
  • Tim1
Epitope
C-Term, AA 1502-1530
17
16
15
5
4
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human
71
18
16
Host
Rabbit
49
16
6
2
Clonality
Polyclonal
Conjugate
Un-conjugated
4
3
3
3
3
3
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
63
45
10
7
4
3
2
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 1502-1530 amino acids from the C-terminal region of human ARHGEF5
Isotype Ig
Specificity This antibody reacts to ARHGEF5.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name ARHGEF5 / TIM (ARHGEF5 Antibody Abstract)
Background Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization.Synonyms: Guanine nucleotide regulatory protein TIM, Oncogene TIM, Rho guanine nucleotide exchange factor 5, Transforming immortalized mammary oncogene, p60 TIM
Gene ID 7984
NCBI Accession NP_005426
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5) (AA 1502-1530), (C-Term) antibody (ABIN950496) ARHGEF5 Antibody (C-term) western blot analysis in A2058 cell line lysates (35µg/lane...
Background publications Wang, Kumamoto, Wang et al.: "Regulation of immature dendritic cell migration by RhoA guanine nucleotide exchange factor Arhgef5." in: The Journal of biological chemistry, Vol. 284, Issue 42, pp. 28599-606, 2009 (PubMed).

Lin, Chang, Yeh et al.: "Disturbance of circadian gene expression in hepatocellular carcinoma." in: Molecular carcinogenesis, Vol. 47, Issue 12, pp. 925-33, 2008 (PubMed).

Zhang, Wolf-Yadlin, Ross et al.: "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules." in: Molecular & cellular proteomics : MCP, Vol. 4, Issue 9, pp. 1240-50, 2005 (PubMed).