ATP Synthase Subunit D (AA 75-105), (Middle Region), (Subunit D) antibody

Catalog No. ABIN950557

Product Details

Target: ATP Synthase Subunit D

Binding Specificity: AA 75-105, Middle Region, Subunit D

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Application: Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Specificity: This antibody reacts to ATP synthase subunit d.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 75-105 amino acids from the Central region of human ATP5H

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details

Target: ATP Synthase Subunit D

Synonyms: ATP synthase D chain antibody, mitochondrial antibody, ATP synthase D chain antibody, ATPQ antibody

Background: Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the d subunit of the Fo complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. In addition, three pseudogenes are located on chromosomes 9, 12 and 15.Synonyms: ATP5H, Complex V subunit d, F1 F0 ATP synthase dubunit d, My032, mitochondria ATP synthase subunit d

Gene ID: 10476

NCBI Accession: NP_001003785