anti-ATP13A2 antibody (ATPase Type 13A2) (C-Term)

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Synonyms RGD1307977, ATP13A2, im:7147302, zgc:136762, CLN12, HSA9947, KRPPD, PARK9, 1110012E06Rik, AA589443
C-Term, AA 1132-1161
(13), (13), (7), (7), (3), (2), (2), (1), (1), (1), (1), (1)
(48), (23), (14)
(44), (6)
This ATP13A2 antibody is un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(34), (16), (13), (11), (3), (3), (2), (1)
Pubmed 5 references available
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Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 1132-1161 amino acids from the C-terminal region of human ATP13A2
Isotype Ig
Specificity This antibody reacts to ATP13A2.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name ATP13A2 / PARK9 (ATP13A2 Antibody Abstract)
Background This gene encodes a member of the P5 subfamily of ATPases which transports inorganic cations as well as other substrates. Mutations in this gene are associated with Kufor-Rakeb syndrome (KRS), also referred to as Parkinson disease 9. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: Probable cation-transporting ATPase 13A2
Gene ID 23400
NCBI Accession NP_001135446
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-ATP13A2 antibody (ATPase Type 13A2) (C-Term) (ABIN950560) ATP13A2 Antibody (C-term) western blot analysis in U251 cell line lysates (35µg/lane)...
Background publications Dos Santos, Pestana, Diniz et al.: "Mutational analysis of GIGYF2, ATP13A2 and GBA genes in Brazilian patients with early-onset Parkinson's disease." in: Neuroscience letters, Vol. 485, Issue 2, pp. 121-4, 2010 (PubMed).

Reetz, Tadic, Kasten et al.: "Structural imaging in the presymptomatic stage of genetically determined parkinsonism." in: Neurobiology of disease, Vol. 39, Issue 3, pp. 402-8, 2010 (PubMed).

Schneider, Paisan-Ruiz, Quinn et al.: "ATP13A2 mutations (PARK9) cause neurodegeneration with brain iron accumulation." in: Movement disorders : official journal of the Movement Disorder Society, Vol. 25, Issue 8, pp. 979-84, 2010 (PubMed).

Fei, Cao, Xiao et al.: "Lack of association between ATP13A2 Ala746Thr variant and Parkinson's disease in Han population of mainland China." in: Neuroscience letters, Vol. 475, Issue 2, pp. 61-3, 2010 (PubMed).

Okada, Kamatani, Takahashi et al.: "A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci." in: Human molecular genetics, Vol. 19, Issue 11, pp. 2303-12, 2010 (PubMed).

Catalog No. ABIN950560
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