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Details for Product No. ABIN950595

BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1) (C-Term), (AA 669-698) antibody

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Synonyms BACH-1, 6230421P05Rik, AI323795, zgc:112205, BACH1
»Alternatives C-Term, AA 669-698
»Alternatives Human
»Alternatives Rabbit
Clonality Polyclonal
»Alternatives ELISA, Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN950595
Quantity 0.4 mL
346.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 669-698 amino acids from the C-terminal region of human BACH1
Specificity This antibody reacts to BACH1.
Purification Affinity chromatography on Protein A
Alternative Name BACH1
Background This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip). The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene.
Alternate names: BTB and CNC homolog 1, HA2303, Transcription regulator protein BACH1, basic leucine zipper transcription factor 1
Gene ID 571
NCBI Accession NP_001177
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) sodium azide as preservative
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Hou, Tian, Zheng et al.: "MicroRNA-196 represses Bach1 protein and hepatitis C virus gene expression in human hepatoma cells expressing hepatitis C viral proteins." in: Hepatology (Baltimore, Md.), Vol. 51, Issue 5, pp. 1494-504, 2010 (PubMed).

Gong, Kim, Leung et al.: "BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control." in: Molecular cell, Vol. 37, Issue 3, pp. 438-46, 2010 (PubMed).

Miyazaki, Kirino, Takeno et al.: "Expression of heme oxygenase-1 in human leukemic cells and its regulation by transcriptional repressor Bach1." in: Cancer science, Vol. 101, Issue 6, pp. 1409-16, 2010 (PubMed).

Alternatives for antigen "BTB and CNC Homology 1, Basic Leucine Zipper Transcription Factor 1 (BACH1)", type "Antibodies"
Hosts (31), (9), (5), (1)
Reactivities (44), (8), (5), (3), (1), (1)
Applications (43), (25), (10), (6), (5), (2), (2), (1), (1)
Epitopes (7), (5), (3), (3), (2), (2), (1), (1), (1), (1), (1)