CUGBP, Elav-Like Family Member 6 (CELF6) (N-Term), (AA 53-82) antibody

Details for Product No. ABIN950681
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Synonyms BRUNOL6, Brunol6, 6330569O16Rik
N-Term, AA 53-82
(2), (2), (1), (1), (1), (1)
Human, Mouse (Murine)
(8), (5), (3), (1)
(8), (1)
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(9), (4), (2), (1), (1)
Pubmed 3 references available
Catalog no. ABIN950681
Quantity 0.4 mL
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Immunogen KLH conjugated synthetic peptide between 53-82 amino acids from the N-terminal region of human BRUNOL6
Specificity This antibody reacts to BRUNOL6.
Purification Affinity chromatography on Protein A
Alternative Name BRUNOL6 / CELF6
Background Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre- mRNA alternative splicing and may also be involved in mRNA editing, and translation. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Alternate names: BRUNOL-6, Bruno-like protein 6, CELF-6, CUG-BP- and ETR-3-like factor 6
Gene ID 60677
NCBI Accession NP_001166155
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) sodium azide as preservative
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Good, Chen, Warner et al.: "A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator." in: The Journal of biological chemistry, Vol. 275, Issue 37, pp. 28583-92, 2000 (PubMed).

Wistow, Bernstein, Wyatt et al.: "Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants." in: Molecular vision, Vol. 8, pp. 205-20, 2002 (PubMed).

Ladd, Nguyen, Malhotra et al.: "CELF6, a member of the CELF family of RNA-binding proteins, regulates muscle-specific splicing enhancer-dependent alternative splicing." in: The Journal of biological chemistry, Vol. 279, Issue 17, pp. 17756-64, 2004 (PubMed).

Hosts (8), (1)
Reactivities (8), (5), (3), (1)
Applications (9), (4), (2), (1), (1)
Epitopes (2), (2), (1), (1), (1), (1)
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