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Details for Product No. ABIN950687

Basic Transcription Factor 3 (BTF3) (N-Term), (AA 1-30) antibody

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Antigen
Synonyms NACB, BTF3a, BTF3b, BETA-NAC, 1700054E11Rik, wu:fb05d06, zgc:153435, BTF3, nacb, btf3a, btf3b, beta-nac, ci-btf3, ATBTF3, F2H15.11, F2H15_11, basic transcription factor 3
Epitope
»Alternatives N-Term, AA 1-30
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN950687
Quantity 0.4 mL
Price
346.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human BTF3
Specificity This antibody reacts to BTF3.
Purification Affinity chromatography on Protein A
Alternative Name BTF3
Background This gene encodes the basic transcription factor 3. This protein forms a stable complex with RNA polymerase IIB and is required for transcriptional initiation. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene has multiple pseudogenes.
Alternate names: NACB, OK/SW-cl.8, RNA polymerase B transcription factor 3, Transcription factor BTF3
Gene ID 689
NCBI Accession NP_001032726
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) sodium azide as preservative
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Harrington, Sherf, Rundlett et al.: "Creation of genome-wide protein expression libraries using random activation of gene expression." in: Nature biotechnology, Vol. 19, Issue 5, pp. 440-5, 2001 (PubMed).

Freire: "Translation initiation factor (iso) 4E interacts with BTF3, the beta subunit of the nascent polypeptide-associated complex." in: Gene, Vol. 345, Issue 2, pp. 271-7, 2005 (PubMed).

Kusumawidjaja, Kayed, Giese et al.: "Basic transcription factor 3 (BTF3) regulates transcription of tumor-associated genes in pancreatic cancer cells." in: Cancer biology & therapy, Vol. 6, Issue 3, pp. 367-76, 2007 (PubMed).

Matsuoka, Ballif, Smogorzewska et al.: "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." in: Science (New York, N.Y.), Vol. 316, Issue 5828, pp. 1160-6, 2007 (PubMed).

Green, Thompson, Johnston et al.: "Interaction between transcription factor, basal transcription factor 3, and the NH2-terminal domain of human estrogen receptor alpha." in: Molecular cancer research : MCR, Vol. 5, Issue 11, pp. 1191-200, 2007 (PubMed).

Alternatives for antigen "Basic Transcription Factor 3 (BTF3)", type "Antibodies"
Hosts (27), (6), (1)
Reactivities (34), (16), (13), (13), (13), (1), (1)
Applications (24), (10), (9), (5), (3), (3), (2), (2), (2), (1)
Conjugates (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (3), (3), (2), (1), (1), (1), (1)
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