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butyrophilin, Subfamily 2, Member A1 (BTN2A1) (AA 343-374), (C-Term) antibody

Details for Product No. ABIN950690, Supplier: Login to see
Antigen
  • BTN2A1
  • btf1
  • bt2.1
  • BTN2A2
  • BK14H9.1
  • BT2.1
  • BTF1
  • DJ3E1.1
Epitope
C-Term, AA 343-374
17
15
4
2
2
1
1
Reactivity
Human
38
2
2
1
Host
Rabbit
34
4
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
29
22
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 343-374 amino acids from the C-terminal region of human BTN2A1
Isotype Ig
Specificity This antibody reacts to BTN2A1.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name BTN2A1 (BTN2A1 Antibody Abstract)
Background BTN2A1 is a member of the BTN2 subfamily of genes, which encode proteins belonging to the butyrophilin protein family. The gene is located in a cluster on chromosome 6, consisting of seven genes belonging to the expanding B7/butyrophilin-like group, a subset of the immunoglobulin gene superfamily. The encoded protein is an integral plasma membrane B box protein involved in lipid, fatty-acid and sterol metabolism. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.Synonyms: BT2.1, BTF1, Butyrophilin subfamily 2 member A1
Gene ID 11120
NCBI Accession NP_001184162
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-butyrophilin, Subfamily 2, Member A1 (BTN2A1) (AA 343-374), (C-Term) antibody (ABIN950690) BTN2A1 Antibody (C-term) western blot analysis in 293 cell line lysates (35µg/lane).T...
Background publications Benyamin, McRae, Zhu et al.: "Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels." in: American journal of human genetics, Vol. 84, Issue 1, pp. 60-5, 2009 (PubMed).

Malcherek, Mayr, Roda-Navarro et al.: "The B7 homolog butyrophilin BTN2A1 is a novel ligand for DC-SIGN." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 6, pp. 3804-11, 2007 (PubMed).

Lamesch, Li, Milstein et al.: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, 2007 (PubMed).

Mungall, Palmer, Sims et al.: "The DNA sequence and analysis of human chromosome 6. ..." in: Nature, Vol. 425, Issue 6960, pp. 805-11, 2003 (PubMed).

Rhodes, Stammers, Malcherek et al.: "The cluster of BTN genes in the extended major histocompatibility complex." in: Genomics, Vol. 71, Issue 3, pp. 351-62, 2001 (PubMed).