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Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 3 (CACNA2D3) (C-Term) antibody

Details for Product No. ABIN950991, Supplier: Login to see
Antigen
  • HSA272268
  • Cacnad3
Epitope
C-Term
17
4
2
Reactivity
Human
25
5
5
Host
Rabbit
24
1
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Western Blotting (WB)
23
15
15
3
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Immunogen KLH conjugated synthetic peptide selected from the C-terminal region of human CACNA2D3
Isotype Ig
Specificity This antibody reacts to CACNA2D3.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name CACNA2D3 (CACNA2D3 Antibody Abstract)
Background CACNA2D3 is a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits.Synonyms: Voltage-dependent calcium channel subunit alpha-2/delta-3, Voltage-gated calcium channel subunit alpha-2/delta-3
Molecular Weight 123011 Da
Gene ID 55799
NCBI Accession NP_060868
Research Area Signaling
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 3 (CACNA2D3) (C-Term) antibody (ABIN950991) CACNA2D3 Antibody (C-term) flow cytometric analysis of HepG2 cells (right histo...
Western Blotting (WB) image for anti-Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 3 (CACNA2D3) (C-Term) antibody (ABIN950991) Western blot analysis of CACNA2D3 Antibody (C-term) in HepG2 cell line lysates ...
Background publications Crawford, Chawla, Houston: "Nanomechanics of biocompatible TiO(2) nanotubes by Interfacial Force Microscopy (IFM)." in: Journal of the mechanical behavior of biomedical materials, Vol. 2, Issue 6, pp. 580-7, 2009 (PubMed).

Trynka, Zhernakova, Romanos et al.: "Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. ..." in: Gut, Vol. 58, Issue 8, pp. 1078-83, 2009 (PubMed).

Uhl, Liu, Drgon et al.: "Molecular genetics of successful smoking cessation: convergent genome-wide association study results." in: Archives of general psychiatry, Vol. 65, Issue 6, pp. 683-93, 2008 (PubMed).

Abo-Dalo, Kim, Roes et al.: "Extensive molecular genetic analysis of the 3p14.3 region in patients with Zimmermann-Laband syndrome." in: American journal of medical genetics. Part A, Vol. 143A, Issue 22, pp. 2668-74, 2007 (PubMed).