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Details for Product No. ABIN950991

Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 3 (CACNA2D3) (C-Term) antibody

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Antigen
Synonyms HSA272268, Cacnad3
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Flow Cytometry (FACS), ELISA, Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN950991
Quantity 0.4 mL
Price
346.50 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide selected from the C-terminal region of human CACNA2D3
Specificity This antibody reacts to CACNA2D3.
Purification Affinity chromatography on Protein A
Alternative Name CACNA2D3
Background CACNA2D3 is a member of the alpha-2/delta subunit family, a protein in the voltage- dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits.
Alternate names: Voltage-dependent calcium channel subunit alpha-2/delta-3, Voltage-gated calcium channel subunit alpha-2/delta-3
Gene ID 55799
NCBI Accession NP_060868
Research Area Signaling
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% (w/v) sodium azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Abo-Dalo, Kim, Roes et al.: "Extensive molecular genetic analysis of the 3p14.3 region in patients with Zimmermann-Laband syndrome." in: American journal of medical genetics. Part A, Vol. 143A, Issue 22, pp. 2668-74, 2007 (PubMed).

Uhl, Liu, Drgon et al.: "Molecular genetics of successful smoking cessation: convergent genome-wide association study results." in: Archives of general psychiatry, Vol. 65, Issue 6, pp. 683-93, 2008 (PubMed).

Trynka, Zhernakova, Romanos et al.: "Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling." in: Gut, Vol. 58, Issue 8, pp. 1078-83, 2009 (PubMed).

Crawford, Chawla, Houston: "Nanomechanics of biocompatible TiO(2) nanotubes by Interfacial Force Microscopy (IFM)." in: Journal of the mechanical behavior of biomedical materials, Vol. 2, Issue 6, pp. 580-7, 2009 (PubMed).

Alternatives for antigen "Calcium Channel, Voltage-Dependent, alpha 2/delta Subunit 3 (CACNA2D3)", type "Antibodies"
Hosts (8), (1)
Reactivities (8), (3), (3)
Applications (9), (3), (3), (2), (2), (1)
Epitopes (4), (3), (2)
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