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CD90 (THY1) antibody (APC)

Details for Product No. ABIN951435
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Antigen
Synonyms CD90, CD7, T25, Thy-1, Thy-1.2, Thy1.1, Thy1.2
Reactivity
Mouse (Murine)
(292), (142), (121), (27), (23), (14), (14), (11), (4), (1), (1)
Host
Mouse
(204), (201), (70), (4)
Clonality (Clone)
Monoclonal ()
Conjugate
APC
(66), (64), (44), (23), (11), (7), (4), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Flow Cytometry (FACS)
(353), (102), (99), (61), (45), (45), (34), (32), (21), (17), (14), (7), (2), (2), (2), (1), (1), (1)
Pubmed 6 references available
Quantity 0.1 mg
Shipping to United States (Change)
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Request Want additional data for this product?

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Catalog No. ABIN951435
456.50 $
Plus shipping costs $45.00

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Immunogen CBA/J. Donor: AKR/J Spleen. Fusion Partner: Spleen from immunized recipient fused with myeloma P3-NSI-1-Ag4-1.
Clone 5a-8
Isotype IgG2b
Specificity This monoclonal antibody reacts with all T lymphocytes from mouse strains expressing the Thy 1.2 phenotype (e.g. C57BL/6, C3H/He, DBA/2, CBA/J, BALB/c), but does not react with lymphocytes expressing the Thy 1.1 phenotype [e.g. AKR/J, B6.PL(74NS)].
Alternative Name CD90
Background CD90 (Thy1) antigen is a GPI linked glycoprotein member of the Immunoglobulin superfamily. It is expressed on murine T cells, thymocytes, neural cells, cells of granulocytic lineage, early hematopoietic progenitors, fibroblasts, neurons and Kupffer's cells. Thy1 may play a role in cell to cell or cell to ligand interactions during synaptogenesis and other events in the brain. It is found in most mouse strains except AKR/J, A, Thy1.1 and B6.PL (74NS) expressing Thy1.1.
Alternate names: CDw90, THY1, Thy-1, Thy-1 membrane glycoprotein
Gene ID 21838
NCBI Accession NP_033408
UniProt P01831
Research Area CD Antigens, Surface Receptors of Immune Cells, Experimental Models
Restrictions For Research Use only
Format Liquid
Concentration 0.2 mg/mL
Buffer PBS containing 0.02% Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8°C. DO NOT FREEZE!
Expiry Date 12 months
Background publications Haba, Nisonoff: "Induction of tolerance to syngeneic IgE in neonatal mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 146, Issue 3, pp. 807-11, 1991 (PubMed).

Krieg, Gourley, Steinberg: "Association of murine lupus and thymic full-length endogenous retroviral expression maps to a bone marrow stem cell." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 146, Issue 9, pp. 3002-5, 1991 (PubMed).

Kruger, Riley: "The age-dependent loss of bone marrow B cell precursors in autoimmune NZ mice results from decreased mitotic activity, but not from inherent stromal cell defects." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 144, Issue 1, pp. 103-10, 1990 (PubMed).

Fine, Silverstone, Gasiewicz: "Impairment of prothymocyte activity by 2,3,7,8-tetrachlorodibenzo-p-dioxin." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 144, Issue 4, pp. 1169-76, 1990 (PubMed).

Ledbetter, Rouse, Micklem et al.: "T cell subsets defined by expression of Lyt-1,2,3 and Thy-1 antigens. Two-parameter immunofluorescence and cytotoxicity analysis with monoclonal antibodies modifies current views." in: The Journal of experimental medicine, Vol. 152, Issue 2, pp. 280-95, 1980 (PubMed).

Radrizzani, Carminatti, Pivetta et al.: "Developmental regulation of Thy 1.2 rate of synthesis in the mouse cerebellum." in: Journal of neuroscience research, Vol. 42, Issue 2, pp. 220-7, 1996 (PubMed).

Validation Images
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