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Cyclin-Dependent Kinase 18 (CDK18) (AA 437-467), (C-Term) antibody

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Synonyms PCTK3, DKFZp468H0312, PCTAIRE, PCTAIRE3, AA682070, Ctk18, Pctk3
C-Term, AA 437-467
(32), (21), (15), (15), (2), (2), (2), (1), (1), (1), (1)
Human, Mouse (Murine)
(40), (32), (6), (2), (2)
(64), (2)
(6), (6), (6), (6), (6), (6)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(60), (45), (14), (3), (1)
Pubmed 5 references available
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Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 437-467 amino acids from the C-terminal region of Human CDK18 / PCTK3
Isotype Ig
Specificity This antibody recognizes Human and Mouse CDK18 / PCTK3 (C-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name CDK18 / PCTK3 (CDK18 Antibody Abstract)
Background PCTK3 may play a role in signal transduction cascades in terminally differentiated cells. Function: May play a role in signal transduction cascades in terminally differentiated cells. Tissue Location: Isoform 3 expression is limited to several subcortical nuclei of the basal gangli and the spinal cord Isoform 2 is widely expressed.Synonyms: Cell division protein kinase 18, Cyclin-dependent kinase 18, PCTAIRE 3, PCTAIRE-3, PCTAIRE-motif protein kinase 3, PCTAIRE3, Serine/threonine-protein kinase PCTAIRE-3
Molecular Weight 54180 Da
Gene ID 5129
NCBI Accession NP_002587
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Cyclin-Dependent Kinase 18 (CDK18) (AA 437-467), (C-Term) antibody (ABIN951447) Western blot analysis of CDK18 / PCTK3 Antibody (C-term) in mouse liver tissue lysate...
Background publications Malumbres, Harlow, Hunt et al.: "Cyclin-dependent kinases: a family portrait." in: Nature cell biology, Vol. 11, Issue 11, pp. 1275-6, 2009 (PubMed).

Wissing, Jänsch, Nimtz et al.: "Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 3, pp. 537-47, 2007 (PubMed).

Herskovits, Davies: "The regulation of tau phosphorylation by PCTAIRE 3: implications for the pathogenesis of Alzheimer's disease." in: Neurobiology of disease, Vol. 23, Issue 2, pp. 398-408, 2006 (PubMed).

Palmer, Konkel, Stephens: "PCTAIRE protein kinases interact directly with the COPII complex and modulate secretory cargo transport." in: Journal of cell science, Vol. 118, Issue Pt 17, pp. 3839-47, 2005 (PubMed).

Herskovits, Davies: "Cloning and expression analysis of two novel PCTAIRE 3 transcripts from human brain." in: Gene, Vol. 328, pp. 59-67, 2004 (PubMed).

Catalog No. ABIN951447
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