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Cyclin-Dependent Kinase 18 (CDK18) (AA 437-467), (C-Term) antibody

Details for Product No. ABIN951447, Supplier: Log in to see
Antigen
  • PCTK3
  • DKFZp468H0312
  • PCTAIRE
  • PCTAIRE3
  • AA682070
  • Ctk18
  • Pctk3
Epitope
C-Term, AA 437-467
32
21
15
15
2
2
2
1
1
1
Reactivity
Human, Mouse (Murine)
40
31
6
2
2
Host
Rabbit
63
2
Clonality
Polyclonal
Conjugate
Un-conjugated
6
6
6
6
6
6
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
59
45
14
3
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 437-467 amino acids from the C-terminal region of Human CDK18 / PCTK3
Isotype Ig
Specificity This antibody recognizes Human and Mouse CDK18 / PCTK3 (C-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name CDK18 / PCTK3 (CDK18 Antibody Abstract)
Background PCTK3 may play a role in signal transduction cascades in terminally differentiated cells. Function: May play a role in signal transduction cascades in terminally differentiated cells. Tissue Location: Isoform 3 expression is limited to several subcortical nuclei of the basal gangli and the spinal cord Isoform 2 is widely expressed.Synonyms: Cell division protein kinase 18, Cyclin-dependent kinase 18, PCTAIRE 3, PCTAIRE-3, PCTAIRE-motif protein kinase 3, PCTAIRE3, Serine/threonine-protein kinase PCTAIRE-3
Molecular Weight 54180 Da
Gene ID 5129
NCBI Accession NP_002587
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Cyclin-Dependent Kinase 18 (CDK18) (AA 437-467), (C-Term) antibody (ABIN951447) Western blot analysis of CDK18 / PCTK3 Antibody (C-term) in mouse liver tissue lysate...
Background publications Malumbres, Harlow, Hunt et al.: "Cyclin-dependent kinases: a family portrait." in: Nature cell biology, Vol. 11, Issue 11, pp. 1275-6, 2009 (PubMed).

Wissing, Jänsch, Nimtz et al.: "Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 3, pp. 537-47, 2007 (PubMed).

Herskovits, Davies: "The regulation of tau phosphorylation by PCTAIRE 3: implications for the pathogenesis of Alzheimer's disease." in: Neurobiology of disease, Vol. 23, Issue 2, pp. 398-408, 2006 (PubMed).

Palmer, Konkel, Stephens: "PCTAIRE protein kinases interact directly with the COPII complex and modulate secretory cargo transport." in: Journal of cell science, Vol. 118, Issue Pt 17, pp. 3839-47, 2005 (PubMed).

Herskovits, Davies: "Cloning and expression analysis of two novel PCTAIRE 3 transcripts from human brain." in: Gene, Vol. 328, pp. 59-67, 2004 (PubMed).