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ARP1 Actin-Related Protein 1 Homolog A, Centractin alpha (Yeast) (ACTR1A) (AA 97-126), (Middle Region) antibody

Details for Product No. ABIN951473, Supplier: Login to see
Antigen
  • ACTR1A
  • arp1
  • centractin
  • ctrn1
  • ARP1
  • CTRN1
  • Arp1
  • alpha-Arp1
Epitope
AA 97-126, Middle Region
15
14
11
10
4
2
2
2
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
55
47
29
3
2
2
1
1
1
1
1
Host
Rabbit
55
11
5
Clonality
Polyclonal
Conjugate
Un-conjugated
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
49
40
11
6
4
Supplier
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Immunogen KLH conjugated synthetic peptide between 97-126 amino acids from the Central region of human ACTR1A
Isotype Ig
Specificity This antibody reacts to Centractin alpha.
Cross-Reactivity (Details) Species reactivity (tested):Mouse.
Purification Affinity chromatography on Protein A
Alternative Name Centractin alpha (ACTR1A Antibody Abstract)
Background This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60 % identical at the amino acid level to conventional actin.Synonyms: ACTR1A, ARP1, Actin-RPV, CTRN1, Centrosome-associated actin homolog
Gene ID 10121
NCBI Accession NP_005727
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-ARP1 Actin-Related Protein 1 Homolog A, Centractin alpha (Yeast) (ACTR1A) (AA 97-126), (Middle Region) antibody (ABIN951473) ACTR1A Antibody (Center) western blot analysis in mouse cerebellum tissue lysates (35...
Background publications Sugarbaker, Richards, Gordon et al.: "Transcriptome sequencing of malignant pleural mesothelioma tumors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 9, pp. 3521-6, 2008 (PubMed).

Petretti, Savoian, Montembault et al.: "The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation." in: EMBO reports, Vol. 7, Issue 4, pp. 418-24, 2006 (PubMed).