ARP1 Actin-Related Protein 1 Homolog A, Centractin alpha (Yeast) (ACTR1A) (AA 97-126), (Middle Region) antibody

Details for Product No. ABIN951473
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Antigen
Synonyms ARP1, CTRN1, arp1, centractin, ctrn1, Arp1, alpha-Arp1, ACTR1A
Epitope
AA 97-126, Middle Region
(15), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(26), (19), (19), (14), (13), (13), (1), (1), (1)
Host
Rabbit
(23), (4)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(16), (10), (9), (3), (1), (1)
Pubmed 2 references available
Catalog no. ABIN951473
Quantity 0.4 mL
Price
357.50 $   Plus shipping costs $45.00
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Immunogen KLH conjugated synthetic peptide between 97-126 amino acids from the Central region of human ACTR1A
Specificity This antibody reacts to Centractin alpha.
Purification Affinity chromatography on Protein A
Alternative Name Centractin alpha
Background This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to- Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin.
Alternate names: ACTR1A, ARP1, Actin-RPV, CTRN1, Centrosome-associated actin homolog
Gene ID 10121
NCBI Accession NP_005727
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) sodium azide as preservative
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Petretti, Savoian, Montembault et al.: "The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation." in: EMBO reports, Vol. 7, Issue 4, pp. 418-24, 2006 (PubMed).

Sugarbaker, Richards, Gordon et al.: "Transcriptome sequencing of malignant pleural mesothelioma tumors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 9, pp. 3521-6, 2008 (PubMed).

Hosts (23), (4)
Reactivities (26), (19), (19), (14), (13), (13), (1), (1), (1)
Applications (16), (10), (9), (3), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (15), (1), (1), (1), (1)
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