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CTF18, Chromosome Transmission Fidelity Factor 18 Homolog (S. Cerevisiae) (CHTF18) (AA 913-943), (C-Term) antibody

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Synonyms CHTF18, zgc:113153, MGC81266, 6030457M03Rik, CTF18, Chl12, C16orf41, C321D2.2, C321D2.3, C321D2.4, CHL12, Ctf18, RUVBL
C-Term, AA 913-943
(16), (15), (4), (4), (2), (2), (2), (1)
(42), (4), (4)
(33), (9)
(2), (2), (2), (2), (2), (2)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(37), (21), (6), (4), (3), (2), (2), (1)
Pubmed 5 references available
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Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 913-943 amino acids from the C-terminal region of human CHTF18
Isotype Ig
Specificity This antibody reacts to CHTF18.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name CHTF18 (CHTF18 Antibody Abstract)
Background CHTF18, CHTF8 (MIM 613202), and DCC1 (DSCC1, MIM 613203) are components of an alternative replication factor C (RFC) (see MIM 600404) complex that loads PCNA (MIM 176740) onto DNA during S phase of the cell cycle (Merkle et al., 2003 [PubMed 12766176], Bermudez et al., 2003 [PubMed 12930902]).Synonyms: C16orf41, CHL12, Chromosome transmission fidelity protein 18 homolog, hCTF18
Molecular Weight 107383 Da
Gene ID 63922
NCBI Accession NP_071375
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-CTF18, Chromosome Transmission Fidelity Factor 18 Homolog (S. Cerevisiae) (CHTF18) (AA 913-943), (C-Term) antibody (ABIN951524) CHTF18 Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (3...
Product cited in: Farina, Shin, Kim et al.: "Studies with the human cohesin establishment factor, ChlR1. Association of ChlR1 with Ctf18-RFC and Fen1." in: The Journal of biological chemistry, Vol. 283, Issue 30, pp. 20925-36, 2008 (PubMed).

Background publications Murakami, Takano, Takeo et al.: "Stable interaction between the human proliferating cell nuclear antigen loader complex Ctf18-replication factor C (RFC) and DNA polymerase {epsilon} is mediated by the cohesion-specific subunits, ..." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34608-15, 2010 (PubMed).

Shiomi, Masutani, Hanaoka et al.: "A second proliferating cell nuclear antigen loader complex, Ctf18-replication factor C, stimulates DNA polymerase eta activity." in: The Journal of biological chemistry, Vol. 282, Issue 29, pp. 20906-14, 2007 (PubMed).

Matsuoka, Ballif, Smogorzewska et al.: "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." in: Science (New York, N.Y.), Vol. 316, Issue 5828, pp. 1160-6, 2007 (PubMed).

Beausoleil, Jedrychowski, Schwartz et al.: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, 2004 (PubMed).

Catalog No. ABIN951524
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