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Details for Product No. ABIN951550

Claudin 4 (CLDN4) (C-Term), (AA 177-206) antibody

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Antigen
Synonyms CPER, CPE-R, CPETR, CPETR1, WBSCR8, hCPE-R, Cep-r, Cpetr, Cpetr1, CLDN4, cper, cpe-r, cpetr, cpetr1, hcpe-r, wbscr8, LOC688420
Epitope
»Alternatives C-Term, AA 177-206
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN951550
Quantity 0.4 mL
Price
346.50 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 177~206 amino acids from the C-terminal region of human CLDN4
Specificity This antibody reacts to CLDN4.
Purification Affinity chromatography on Protein A
Alternative Name Claudin-4 / CLDN4
Background CLDN4 is an integral membrane protein, which belongs to the claudin family. The protein is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life.
Alternate names: CPE-R, CPE-Receptor, CPER, CPETR1, Clostridium perfringens enterotoxin receptor, WBSCR8, Williams-Beuren syndrome chromosomal region 8 protein
Gene ID 1364
NCBI Accession NP_001296
Research Area Cytoskeleton
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% (w/v) sodium azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Robertson, Smedley, McClane: "Identification of a claudin-4 residue important for mediating the host cell binding and action of Clostridium perfringens enterotoxin." in: Infection and immunity, Vol. 78, Issue 1, pp. 505-17, 2009 (PubMed).

Kimura, Abe, Kamitani et al.: "Clostridium perfringens enterotoxin interacts with claudins via electrostatic attraction." in: The Journal of biological chemistry, Vol. 285, Issue 1, pp. 401-8, 2009 (PubMed).

Papageorgis, Lambert, Ozturk et al.: "Smad signaling is required to maintain epigenetic silencing during breast cancer progression." in: Cancer research, Vol. 70, Issue 3, pp. 968-78, 2010 (PubMed).

Seckin, Arici, Harputluoglu et al.: "Expression of claudin-4 and beta-catenin in gastric premalignant lesions." in: Acta gastro-enterologica Belgica, Vol. 72, Issue 4, pp. 407-12, 2010 (PubMed).

Alternatives for antigen "Claudin 4 (CLDN4)", type "Antibodies"
Hosts (76), (15)
Reactivities (89), (47), (35), (18), (18), (17), (17), (1), (1)
Applications (42), (36), (36), (18), (15), (10), (4), (4), (2), (2), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (36), (4), (3), (2), (2), (1), (1)
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