C-Type Lectin Domain Family 18, Member A (CLEC18A) (C-Term), (AA 345-375) antibody

Details for Product No. ABIN951563
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Antigen
Synonyms MRCL, MRCL1, MRLP2, Mrcl
Epitope
C-Term, AA 345-375
(7), (6)
Reactivity
Human
(14), (3), (3)
Host
Rabbit
(14)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(14), (12), (8), (1)
Pubmed 2 references available
Quantity 0.4 mL
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Catalog No. ABIN951563
357.50 $
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Immunogen KLH conjugated synthetic peptide between 345-375 amino acids from the C-terminal region of Human CLEC18A Genename: CLEC18A
Specificity This antibody detects CLEC18A at C-term.
Purification Affinity Chromatography on Protein A
Alternative Name CLEC18A
Background The C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily consists of a variety of proteins that share a common protein fold and have diverse functions, including cell-cell signaling, cell adhesion, glycoprotein turnover and immune responses. CLEC-18 (C-type lectin domain family 18) exists as three nearly identical forms, designated CLEC-18A, CLEC-18B and CLEC-18C, or mannose receptor-like protein 1, 2 and 3, respectively. Both CLEC-18A and CLEC-18C contain 446 amino acids, whereas CLEC-18B contains 455 amino acids, all three forms are secreted proteins that contain one C-type lectin domain, a SCP domain and a single EGF-like domain. All three CLEC-18 proteins exist as two alternatively spliced isoforms that are encoded by genes that map to human chromosome 16q22.
Alternate names: C-type lectin domain family 18 member A, MRLP2, Mannose receptor-like protein 2
Gene ID 348174
NCBI Accession NP_001129686
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% (w/v) Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Clark, Gurney, Abaya et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).

Lamesch, Li, Milstein et al.: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, 2007 (PubMed).

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