C-Type Lectin Domain Family 2, Member A (CLEC2A) (AA 79-107), (Middle Region) antibody

Details for Product No. ABIN951564
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Antigen
Synonyms KACL, PILAR, UNQ5792
Epitope
AA 79-107, Middle Region
(8), (7), (6), (2)
Reactivity
Human
(20)
Host
Rabbit
(20)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
(20), (11), (1), (1)
Pubmed 5 references available
Quantity 0.4 mL
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Catalog No. ABIN951564
357.50 $
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Immunogen KLH conjugated synthetic peptide between 79-107 amino acids from the Central region of human CLEC2A
Isotype Ig
Specificity This antibody reacts to CLEC2A.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name CLEC2A
Background CLEC2A belongs to the CLEC2 family of activation-induced, natural killer gene complex-encoded C-type lectin-like receptors (Spreu et al., 2007 [PubMed 18046548]).Synonyms: C-type lectin domain family 2 member A
Molecular Weight 19972 Da
Gene ID 387836
NCBI Accession NP_001124183
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Clark, Gurney, Abaya et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).

Spreu, Kienle, Schrage et al.: "CLEC2A: a novel, alternatively spliced and skin-associated member of the NKC-encoded AICL-CD69-LLT1 family." in: Immunogenetics, Vol. 59, Issue 12, pp. 903-12, 2007 (PubMed).

Rerkasem, Gallagher, Grimble et al.: "Managing hypercholesterolemia and its correlation with carotid plaque morphology in patients undergoing carotid endarterectomy." in: Vascular health and risk management, Vol. 4, Issue 6, pp. 1259-64, 2009 (PubMed).

Ozaki, Suzuki-Inoue, Inoue: "Novel interactions in platelet biology: CLEC-2/podoplanin and laminin/GPVI." in: Journal of thrombosis and haemostasis : JTH, Vol. 7 Suppl 1, pp. 191-4, 2009 (PubMed).

Spreu, Kuttruff, Stejfova et al.: "Interaction of C-type lectin-like receptors NKp65 and KACL facilitates dedicated immune recognition of human keratinocytes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 11, pp. 5100-5, 2010 (PubMed).

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