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Component of Oligomeric Golgi Complex 3 (COG3) (AA 673-703), (C-Term) antibody

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Synonyms CG 3248, CG3248, COG3, Dmel\\CG3248, SEC34, dCOG3, E430004N23
C-Term, AA 673-703
(16), (15), (2), (2), (2), (2), (1), (1), (1), (1)
(33), (6), (6)
(27), (6)
(2), (2), (2), (2), (2), (2)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(30), (22), (7), (1), (1)
Pubmed 5 references available
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Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 673-703 amino acids from the C-terminal region of human COG3.
Isotype Ig
Specificity This antibody reacts to COG3.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name COG3 (COG3 Antibody Abstract)
Background The protein encoded by this gene has similarity to a yeast protein. It seems to be part of a peripheral membrane protein complex localized on cis/medial Golgi cisternae where it may participate in tethering intra-Golgi transport vesicles. [provided by RefSeq].Synonyms: COG complex subunit 3, Component of oligomeric Golgi complex 3, Conserved oligomeric Golgi complex subunit 3, SEC34, Vesicle-docking protein SEC34 homolog, p94
Molecular Weight 94096 Da
Gene ID 83548
NCBI Accession NP_001191405
Research Area Signaling, Organelles
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Component of Oligomeric Golgi Complex 3 (COG3) (AA 673-703), (C-Term) antibody (ABIN951616) COG3 Antibody (C-term) western blot analysis in Hela cell line lysates (35µg/la...
Background publications Laufman, Kedan, Hong et al.: "Direct interaction between the COG complex and the SM protein, Sly1, is required for Golgi SNARE pairing." in: The EMBO journal, Vol. 28, Issue 14, pp. 2006-17, 2009 (PubMed).

Shestakova, Zolov, Lupashin: "COG complex-mediated recycling of Golgi glycosyltransferases is essential for normal protein glycosylation." in: Traffic (Copenhagen, Denmark), Vol. 7, Issue 2, pp. 191-204, 2006 (PubMed).

Dunham, Matthews, Burton et al.: "The DNA sequence and analysis of human chromosome 13. ..." in: Nature, Vol. 428, Issue 6982, pp. 522-8, 2004 (PubMed).

Loh, Hong: "The binary interacting network of the conserved oligomeric Golgi tethering complex." in: The Journal of biological chemistry, Vol. 279, Issue 23, pp. 24640-8, 2004 (PubMed).

Gevaert, Goethals, Martens et al.: "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides." in: Nature biotechnology, Vol. 21, Issue 5, pp. 566-9, 2003 (PubMed).

Catalog No. ABIN951616
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