CUB and Zona Pellucida-Like Domains 1 (CUZD1) (AA 586-614), (C-Term) antibody

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Antigen
Synonyms ERG-1, UO-44, Erg-1, Itmap1, Uo-44, Usg, Utczp, ERG1, Uo
Epitope
C-Term, AA 586-614
(17), (15), (7), (5), (5), (2)
Reactivity
Human
(26), (5), (5)
Host
Rabbit
(35), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(5), (5), (2), (2), (2), (2)
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(30), (27), (16), (13), (10), (9), (7), (1)
Pubmed 5 references available
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Quantity 0.4 mL
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Immunogen KLH conjugated synthetic peptide between 586-614 amino acids from the C-terminal region of human CUZD1
Isotype Ig
Specificity This antibody reacts to CUZD1.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name CUZD1 (CUZD1 Antibody Abstract)
Background Potent and specific cellular inhibitor of CaM-kinase II (CAMK2). Traps Ca(2+)/calmodulin on CAMK2. May play an important role in the regulation of cell growth when overexpressed in colon adenocarcinoma LoVo cells. Traps Ca(2+)/calmodulin on CAMK2.Synonyms: CUB and ZP domain-containing protein 1, CUB and zona pellucida-like domain-containing protein 1
Molecular Weight 68153 Da, Isoform 36kd Da
Gene ID 50624
NCBI Accession NP_071317
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunofluorescence (IF) image for anti-CUB and Zona Pellucida-Like Domains 1 (CUZD1) (AA 586-614), (C-Term) antibody (ABIN951734) Confocal immunofluorescent analysis of CUZD1 Antibody (C-term)(Cat#AP51141PU-N) with ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-CUB and Zona Pellucida-Like Domains 1 (CUZD1) (AA 586-614), (C-Term) antibody (ABIN951734) CUZD1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin ...
Western Blotting (WB) image for anti-CUB and Zona Pellucida-Like Domains 1 (CUZD1) (AA 586-614), (C-Term) antibody (ABIN951734) CUZD1 Antibody (C-term) western blot analysis in 293 cell line lysates (35µg/lane).Th...
Background publications Leong, Ong, Tay et al.: "Silencing expression of UO-44 (CUZD1) using small interfering RNA sensitizes human ovarian cancer cells to cisplatin in vitro." in: Oncogene, Vol. 26, Issue 6, pp. 870-80, 2007 (PubMed).

Blanchetot, Chagnon, Dubé et al.: "Substrate-trapping techniques in the identification of cellular PTP targets." in: Methods (San Diego, Calif.), Vol. 35, Issue 1, pp. 44-53, 2004 (PubMed).

Leong, Ng, Ong et al.: "Molecular cloning, characterization and isolation of novel spliced variants of the human ortholog of a rat estrogen-regulated membrane-associated protein, UO-44." in: Oncogene, Vol. 23, Issue 33, pp. 5707-18, 2004 (PubMed).

Deloukas, Earthrowl, Grafham et al.: "The DNA sequence and comparative analysis of human chromosome 10. ..." in: Nature, Vol. 429, Issue 6990, pp. 375-81, 2004 (PubMed).

Clark, Gurney, Abaya et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).

Catalog No. ABIN951734
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