Cysteinyl Leukotriene Receptor 1 (CYSLTR1) (AA 143-172), (Middle Region) antibody

Details for Product No. ABIN951788
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

 
Antigen
Synonyms CYSLTR1, Cyslt1, CYSLT1, CYSLT1R, CYSLTR, HMTMF81, CysLT1R, BB147369, cysLT1R, zgc:112062
Epitope
AA 143-172, Middle Region
(5), (5), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(37), (2), (1)
Host
Rabbit
(36), (2)
Clonality
Polyclonal
Application
ELISA, Western Blotting (WB)
(31), (19), (16), (13), (7), (2), (1)
Pubmed 3 references available
Catalog no. ABIN951788
Quantity 0.4 mL
Price
357.50 $   Plus shipping costs $45.00
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen KLH conjugated synthetic peptide between 143-172 amino acids from the Central region of Human CYSLTR1. Genename: CYSLTR1
Specificity This antibody recognizes Human CYSLTR1 (Center).
Purification Affinity Chromatography on Protein A
Alternative Name CYSLTR1
Background The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.
Alternate names: CysLTR1, Cysteinyl leukotriene D4 receptor, Cysteinyl leukotriene receptor 1, G-protein coupled receptor HG55, HG55, HMTMF81, LTD4 receptor
Molecular Weight 38541 Da
Gene ID 10800
NCBI Accession NP_006630
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% Sodium Azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Boulay, Duchesneau, Jacques et al.: "CysLT1-R expression following allergen provocation in asthma and allergic rhinitis." in: Prostaglandins, leukotrienes, and essential fatty acids, Vol. 83, Issue 1, pp. 15-22, 2010 (PubMed).

Schuurhof, Bont, Siezen et al.: "Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls." in: Pediatric pulmonology, Vol. 45, Issue 6, pp. 608-13, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Hosts (36), (2)
Reactivities (37), (2), (1)
Applications (31), (19), (16), (13), (7), (2), (1)
Epitopes (5), (5), (2), (2), (1), (1), (1), (1), (1)
back to top