Cysteine-Rich Protein 2 (CRIP2) (C-Term), (AA 178-208) antibody

Details for Product No. ABIN951794
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Synonyms 0610010I23Rik, AW743261, C77570, CRP2, CRP4, Crp, ESP1, Hlp, CRIP, wu:fb30h10, zgc:55408
C-Term, AA 178-208
(23), (21), (3), (2), (2), (1), (1)
(39), (4), (4), (2), (1)
(37), (2)
(4), (4), (4), (3), (3), (3)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(39), (22), (6), (3), (3), (2), (1)
Pubmed 5 references available
Quantity 0.4 mL
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Catalog No. ABIN951794
357.50 $
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Immunogen KLH conjugated synthetic peptide between 178-208 amino acids from the C-terminal region of human CRIP2
Isotype Ig
Specificity This antibody reacts to human CRIP2.
Purification Affinity chromatography on Protein A
Alternative Name Cysteine-Rich Protein 2
Background CRIP2 is a 208-amino acid protein containing 2 LIM domains and shares 93 % amino acid sequence identity with its rat homolog, called Esp1 or Crp2. Northern blot analysis showed widespread tissue expression of the 1.3-kb CRIP2 mRNA, with the highest level of expression found in heart. In testis, a second 1.7-kb mRNA was also detected.Synonyms: CRIP2, CRP2, Protein ESP1
Molecular Weight 22493 Da
Gene ID 1397
NCBI Accession NP_001303
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Tanabe, Hotoda, Sasagawa et al.: "ADAM19 autolysis is activated by LPS and promotes non-classical secretion of cysteine-rich protein 2." in: Biochemical and biophysical research communications, Vol. 396, Issue 4, pp. 927-32, 2010 (PubMed).

Rikova, Guo, Zeng et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. ..." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).

Kiechl, Werner, Knoflach et al.: "The osteoprotegerin/RANK/RANKL system: a bone key to vascular disease." in: Expert review of cardiovascular therapy, Vol. 4, Issue 6, pp. 801-11, 2006 (PubMed).

van Ham, Croes, Schepens et al.: "Cloning and characterization of mCRIP2, a mouse LIM-only protein that interacts with PDZ domain IV of PTP-BL." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 8, Issue 7, pp. 631-44, 2003 (PubMed).

Chang, Belaguli, Iyer et al.: "Cysteine-rich LIM-only proteins CRP1 and CRP2 are potent smooth muscle differentiation cofactors." in: Developmental cell, Vol. 4, Issue 1, pp. 107-18, 2003 (PubMed).

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