Cysteine-Rich Protein 2 (CRIP2) (C-Term), (AA 178-208) antibody

Details for Product No. ABIN951794
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Antigen
Synonyms 0610010I23Rik, AW743261, C77570, CRP2, CRP4, Crp, ESP1, Hlp, CRIP, wu:fb30h10, zgc:55408
Epitope
C-Term, AA 178-208
(8), (7), (2), (2), (2), (1), (1)
Reactivity
Human
(19), (4), (4), (2), (1)
Host
Rabbit
(18), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
(19), (9), (3), (3), (2)
Pubmed 5 references available
Quantity 0.4 mL
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Catalog No. ABIN951794
357.50 $
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Immunogen KLH conjugated synthetic peptide between 178-208 amino acids from the C-terminal region of human CRIP2
Isotype Ig
Specificity This antibody reacts to human CRIP2.
Purification Affinity chromatography on Protein A
Alternative Name Cysteine-Rich Protein 2
Background CRIP2 is a 208-amino acid protein containing 2 LIM domains and shares 93 % amino acid sequence identity with its rat homolog, called Esp1 or Crp2. Northern blot analysis showed widespread tissue expression of the 1.3-kb CRIP2 mRNA, with the highest level of expression found in heart. In testis, a second 1.7-kb mRNA was also detected.Synonyms: CRIP2, CRP2, Protein ESP1
Molecular Weight 22493 Da
Gene ID 1397
NCBI Accession NP_001303
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Chang, Belaguli, Iyer et al.: "Cysteine-rich LIM-only proteins CRP1 and CRP2 are potent smooth muscle differentiation cofactors." in: Developmental cell, Vol. 4, Issue 1, pp. 107-18, 2003 (PubMed).

van Ham, Croes, Schepens et al.: "Cloning and characterization of mCRIP2, a mouse LIM-only protein that interacts with PDZ domain IV of PTP-BL." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 8, Issue 7, pp. 631-44, 2003 (PubMed).

Kiechl, Werner, Knoflach et al.: "The osteoprotegerin/RANK/RANKL system: a bone key to vascular disease." in: Expert review of cardiovascular therapy, Vol. 4, Issue 6, pp. 801-11, 2006 (PubMed).

Rikova, Guo, Zeng et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. ..." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).

Tanabe, Hotoda, Sasagawa et al.: "ADAM19 autolysis is activated by LPS and promotes non-classical secretion of cysteine-rich protein 2." in: Biochemical and biophysical research communications, Vol. 396, Issue 4, pp. 927-32, 2010 (PubMed).

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