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Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2) (AA 587-617), (C-Term) antibody

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Synonyms Xdsh, dishevelled, dsh, dvl, Dvl-2, xdsh, wu:fc05d12, wu:fo71e09, wu:fp54a02, zgc:55372
C-Term, AA 587-617
(20), (15), (14), (13), (13), (13), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1)
(95), (42), (37), (2), (2), (2), (2), (1), (1), (1), (1), (1)
(80), (18)
(5), (5), (4), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(59), (26), (23), (15), (11), (7), (4)
Pubmed 4 references available
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Quantity 0.4 mL
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Immunogen KLH conjugated synthetic peptide between 587-617 amino acids from the C-terminal region of Human DVL2.
Isotype Ig
Specificity This antibody recognizes Human Dishevelled-2 / DVL2 (C-term).
Purification Affinity Chromatography on Protein A
Alternative Name Dishevelled-2 / DVL2 (DVL2 Antibody Abstract)
Background This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40 % amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.Synonyms: DSH homolog 2, DVL-2, Segment polarity protein dishevelled homolog DVL-2
Molecular Weight 78948 Da
Gene ID 1856
NCBI Accession NP_004413
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2) (AA 587-617), (C-Term) antibody (ABIN951919) Western blot analysis of Dishevelled-2 / DVL2 Antibody (C-term) in CEM cell line lysa...
Background publications Ohashi, Yamamoto, Horiguchi et al.: "Association between visceral adipose tissue area and coronary plaque morphology assessed by CT angiography." in: JACC. Cardiovascular imaging, Vol. 3, Issue 9, pp. 908-17, 2010 (PubMed).

Kikuchi, Niikura, Kitagawa et al.: "Dishevelled, a Wnt signalling component, is involved in mitotic progression in cooperation with Plk1." in: The EMBO journal, Vol. 29, Issue 20, pp. 3470-83, 2010 (PubMed).

Gao, Cao, Bao et al.: "Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation." in: Nature cell biology, Vol. 12, Issue 8, pp. 781-90, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Catalog No. ABIN951919
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