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Discs, Large (Drosophila) Homolog-Associated Protein 4 (DLGAP4) (AA 104-133), (N-Term) antibody

Details for Product No. ABIN951921, Supplier: Log in to see
Antigen
  • MGC155295
  • dlgap4
  • zgc:171808
  • DKFZp469I1627
  • DAP4
  • DLP4
  • RP5-977B1.6
  • SAPAP4
  • DAP-4
  • Dap4
  • AI225853
  • BC024558
  • SAPAP-4
  • Sapap4
  • WBP16
Epitope
N-Term, AA 104-133
16
15
4
3
3
2
2
1
Reactivity
Human
46
13
13
Host
Rabbit
42
4
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
34
19
11
7
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 104-133 amino acids from the N-terminal region of Human DLGAP4
Isotype Ig
Specificity This antibody recognizes Human DLGAP4 / SAPAP4 (N-term).
Purification Affinity chromatography on Protein A
Alternative Name DLGAP4 / SAPAP4 (DLGAP4 Antibody Abstract)
Background DLGAP4 is a membrane-associated guanylate kinase found at the postsynaptic density in neuronal cells. It is a signaling molecule that can interact with potassium channels and receptors, as well as other signaling molecules. The protein encoded by this gene can interact with PSD-95 through its guanylate kinase domain and may be involved in clustering PSD-95 in the postsynaptic density region. The encoded protein is one of at least four similar proteins that have been found. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.Synonyms: DAP-4, DAP4, Disks large-associated protein 4, KIAA0964, PSD-95/SAP90-binding protein 4, SAP90/PSD-95-associated protein 4
Molecular Weight 108012 Da
Gene ID 22839
NCBI Accession NP_001035951
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Discs, Large (Drosophila) Homolog-Associated Protein 4 (DLGAP4) (AA 104-133), (N-Term) antibody (ABIN951921) Western blot analysis of DLGAP4 / SAPAP4 Antibody (N-term) in NCI-H292 cell line lysa...
Background publications Gratacòs, Costas, de Cid et al.: "Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 150B, Issue 6, pp. 808-16, 2009 (PubMed).

Rikova, Guo, Zeng et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. ..." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).

Sugiyama, Masuda, Shinoda et al.: "Phosphopeptide enrichment by aliphatic hydroxy acid-modified metal oxide chromatography for nano-LC-MS/MS in proteomics applications." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 6, pp. 1103-9, 2007 (PubMed).