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DnaJ (Hsp40) Homolog, Subfamily B, Member 11 (DNAJB11) (N-Term), (AA 62-92) antibody

Details for Product No. ABIN951941
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Antigen
Synonyms MGC75796, MGC81924, ABBP-2, ABBP2, DJ9, Dj-9, EDJ, ERdj3, ERj3, ERj3p, PRO1080, UNQ537, hDj-9, 1810031F23Rik, AL024055, Dj9, LRRGT00084, cb954
Epitope
N-Term, AA 62-92
(8), (7), (3), (2), (2), (1), (1)
Reactivity
Human
(26), (13), (13), (1), (1), (1)
Host
Rabbit
(27)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
(27), (21), (17), (4), (3)
Pubmed 3 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
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Catalog No. ABIN951941
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Immunogen KLH conjugated synthetic peptide between 62-92 amino acids from the N-terminal region of Human DNAJB11 Genename: DNAJB11
Specificity This antibody recognizes Human DNAJB11 (N-term).
Purification Affinity Chromatography on Protein A
Alternative Name DNAJB11
Background DNAJB11 belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus, a glycine/phenylalanine (G/F)-rich region, and a C-terminal cysteine-rich region (Ohtsuka and Hata, 2000 [PubMed 11147971]).
Alternate names: APOBEC1-binding protein 2, DnaJ homolog subfamily B member 11, EDJ, ER-associated DNAJ, ER-associated Hsp40 co-chaperone, ER-associated dnaJ protein 3, ERJ3, ERdj3, ERj3p, HEDJ, PSEC0121, PWP1-interacting protein 4, hDj9
Molecular Weight 40514 Da
Gene ID 51726
NCBI Accession NP_057390
Research Area Signaling, Heat Shock Proteins
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Bernal-Bayard, Cardenal-Muñoz, Ramos-Morales: "The Salmonella type III secretion effector, salmonella leucine-rich repeat protein (SlrP), targets the human chaperone ERdj3." in: The Journal of biological chemistry, Vol. 285, Issue 21, pp. 16360-8, 2010 (PubMed).

Wen, Damania: "Hsp90 and Hsp40/Erdj3 are required for the expression and anti-apoptotic function of KSHV K1." in: Oncogene, Vol. 29, Issue 24, pp. 3532-44, 2010 (PubMed).

Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Validation Images
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