Dynein, Axonemal, Light Intermediate Chain 1 (DNALI1) (C-Term), (AA 214-243) antibody

Details for Product No. ABIN951953
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Antigen
Synonyms zgc:171493, zgc:171595, P28, dJ423B22.5, hp28, 1700023A09Rik, AW049135
Epitope
C-Term, AA 214-243
(9), (7), (5), (3), (1)
Reactivity
Human
(26), (9), (7), (2), (2), (1), (1)
Host
Rabbit
(22), (4)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(25), (11), (5), (4), (3), (1), (1), (1)
Pubmed 3 references available
Quantity 0.4 mL
Shipping to United States (Change)
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Catalog No. ABIN951953
357.50 $
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Immunogen conjugated synthetic peptide between 214-243 amino acids from the C-terminal region of Human DNALI1.
Specificity This antibody recognizes Human DNALI1 (C-term).
Purification Affinity Chromatography on Protein A
Alternative Name DNALI1
Background This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects.
Alternate names: Axonemal dynein light intermediate polypeptide 1, HP28, Inner dynein arm light chain axonemal
Molecular Weight 29662 Da
Gene ID 7802
NCBI Accession NP_003453
Research Area Signaling, Cytoskeleton
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Hanna, Kruskal, Ezekowitz et al.: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, 1996 (PubMed).

Kastury, Taylor, Shen et al.: "Complementary deoxyribonucleic acid cloning and characterization of a putative human axonemal dynein light chain gene." in: The Journal of clinical endocrinology and metabolism, Vol. 82, Issue 9, pp. 3047-53, 1997 (PubMed).

Combs, Kim, Tan et al.: "Recruitment of dynein to the Jurkat immunological synapse." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 40, pp. 14883-8, 2006 (PubMed).

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