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Details for Product No. ABIN951976

DnaJ (Hsp40) Homolog, Subfamily C, Member 24 (DNAJC24) (AA 53-82), (Middle Region) antibody

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Antigen
Synonyms DPH4, JJJ3, ZCSL3, 1700030A21Rik, 2610027M02Rik, AV066965, AW240712, Dph4, MmDjC7, Zcsl3, RGD1564710
Epitope
»Alternatives AA 53-82, Middle Region
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN951976
Quantity 0.4 mL
Price
346.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 53-82 amino acids from the Central region of Human DPH4 Genename: DNAJC24
Specificity This antibody recognizes Human DPH4 (Center).
Purification Affinity Chromatography on Protein A
Alternative Name DPH4
Background Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM].
Alternate names: DNAJC24, DnaJ homolog subfamily C member 24, ZCSL3
Molecular Weight 17008 Da
Gene ID 120526
NCBI Accession NP_859057
Research Area Signaling, Metabolism, Heat Shock Proteins
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Liu, Milne, Kuremsky et al.: "Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2." in: Molecular and cellular biology, Vol. 24, Issue 21, pp. 9487-97, 2004 (PubMed).

Alternatives for antigen "DnaJ (Hsp40) Homolog, Subfamily C, Member 24 (DNAJC24)", type "Antibodies"
Hosts (9)
Reactivities (8), (3), (2), (1)
Applications (9), (4)
Epitopes (2), (2), (2), (1), (1), (1)
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