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DnaJ (Hsp40) Homolog, Subfamily C, Member 24 (DNAJC24) (AA 53-82), (Middle Region) antibody

Details for Product No. ABIN951976, Supplier: Log in to see
Antigen
  • DPH4
  • JJJ3
  • ZCSL3
  • 1700030A21Rik
  • 2610027M02Rik
  • AV066965
  • AW240712
  • Dph4
  • MmDjC7
  • Zcsl3
  • RGD1564710
Epitope
AA 53-82, Middle Region
15
15
11
3
2
1
Reactivity
Human
29
6
5
1
Host
Rabbit
29
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
27
21
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 53-82 amino acids from the Central region of Human DPH4 Genename: DNAJC24
Isotype Ig
Specificity This antibody recognizes Human DPH4 (Center).
Purification Affinity Chromatography on Protein A
Alternative Name DPH4 (DNAJC24 Antibody Abstract)
Background Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2, MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM].Synonyms: DNAJC24, DnaJ homolog subfamily C member 24, ZCSL3
Molecular Weight 17008 Da
Gene ID 120526
NCBI Accession NP_859057
Research Area Signaling, Metabolism, Heat Shock Proteins
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 24 (DNAJC24) (AA 53-82), (Middle Region) antibody (ABIN951976) Western blot analysis of DPH4 Antibody  in HL-60 cell line lysates (35ug/lane). This ...
Background publications Liu, Milne, Kuremsky et al.: "Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2." in: Molecular and cellular biology, Vol. 24, Issue 21, pp. 9487-97, 2004 (PubMed).