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F-Box Protein 3 (FBXO3) (AA 401-431), (C-Term) antibody

Details for Product No. ABIN952286, Supplier: Log in to see
Antigen
  • zgc:112485
  • DKFZp459H187
  • FBA
  • FBX3
  • 1200002G09Rik
  • 1700026K02Rik
  • AI046358
  • Fba
Epitope
C-Term, AA 401-431
16
9
8
4
2
1
Reactivity
Human
31
6
6
2
1
Host
Rabbit
28
3
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Western Blotting (WB)
28
19
16
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 401~431 amino acids from the C-terminal region of human FBXO3.
Isotype Ig
Specificity This antibody recognizes Human FBXO3 (C-term).
Purification Affinity Chromatography on Protein A
Alternative Name FBXO3 (FBXO3 Antibody Abstract)
Background FBXO3 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs.Synonyms: F-box only protein 3, FBX3
Molecular Weight 54561 Da
Gene ID 26273
NCBI Accession NP_036307
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-F-Box Protein 3 (FBXO3) (AA 401-431), (C-Term) antibody (ABIN952286) Flow cytometric analysis of HepG2 cells using FBXO3 Antibody (C-term) Cat.-No AP51629...
Western Blotting (WB) image for anti-F-Box Protein 3 (FBXO3) (AA 401-431), (C-Term) antibody (ABIN952286) Western blot analysis of FBXO3 Antibody (C-term) in HepG2 cell line lysates (35ug/lan...
Background publications Shima, Shima, Chiba et al.: "PML activates transcription by protecting HIPK2 and p300 from SCFFbx3-mediated degradation." in: Molecular and cellular biology, Vol. 28, Issue 23, pp. 7126-38, 2008 (PubMed).

Ilyin, Rialland, Pigeon et al.: "cDNA cloning and expression analysis of new members of the mammalian F-box protein family." in: Genomics, Vol. 67, Issue 1, pp. 40-7, 2000 (PubMed).