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FEZ Family Zinc Finger 1 (FEZF1) (AA 67-96), (N-Term) antibody

Details for Product No. ABIN952301, Supplier: Login to see
Antigen
  • RGD1560480
  • fezf
  • znf312b
  • MGC145310
  • FEZ
  • ZNF312B
  • 3110069A13Rik
  • Fez
  • Zfp312-like
  • fez-like
  • fez
  • fezf2
  • wu:fc29c05
  • wu:fc89h05
  • zgc:153730
Epitope
N-Term, AA 67-96
17
14
4
Reactivity
Human, Mouse (Murine)
35
17
13
Host
Rabbit
36
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
25
17
11
3
2
Supplier
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Immunogen KLH conjugated synthetic peptide between 67-96 amino acids from the N-terminal region of human FEZF1
Isotype Ig
Specificity This antibody reacts to FEZF1.
Cross-Reactivity (Details) Species reactivity (tested):Human and Mouse.
Purification Affinity chromatography on Protein A
Alternative Name FEZF1 (FEZF1 Antibody Abstract)
Background Transcription repressor. Involved in the axonal projection and proper termination of olfactory sensory neurons (OSN). Plays a role in rostro-caudal patterning of the diencephalon and in prethalamic formation. Expression is required in OSN to cell-autonomously regulate OSN axon projections. Regulates non-cell-autonomously the layer formation of the olfactory bulb development and the interneurons. May be required for correct rostral migration of the interneuron progenitors. FEZF1 is expressed in brain. Little or no expression in other tissues. Overexpressed specifically in gastric cancers. A 2-to 20-fold increase is found in over 50 % of gastric cancer tissues. Subcellular location of FEZF1 is in the nucleus.Synonyms: FEZ, Fez family zinc finger protein 1, ZNF312B, Zinc finger protein 312B
Molecular Weight 52038 Da
Gene ID 389549
NCBI Accession NP_001019784
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-FEZ Family Zinc Finger 1 (FEZF1) (AA 67-96), (N-Term) antibody (ABIN952301) FEZF1 Antibody (N-term) western blot analysis in mouse stomach tissue lysates (35µg/l...
Background publications Maestrini, Pagnamenta, Lamb et al.: "High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility." in: Molecular psychiatry, Vol. 15, Issue 9, pp. 954-68, 2010 (PubMed).

Song, Oh, Kim et al.: "Human ZNF312b promotes the progression of gastric cancer by transcriptional activation of the K-ras gene." in: Cancer research, Vol. 69, Issue 7, pp. 3131-9, 2009 (PubMed).