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FYVE, RhoGEF and PH Domain Containing 6 (FGD6) (AA 1331-1359), (C-Term) antibody

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Synonyms ZFYVE24, AA123052, Etohd4
C-Term, AA 1331-1359
(15), (15), (2), (1), (1), (1), (1)
(19), (3)
(2), (2), (2), (2), (2), (2)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(21), (16), (14), (2)
Pubmed 2 references available
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Quantity 0.4 mL
Shipping to United States ( )
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Immunogen KLH conjugated synthetic peptide between 1331-1359 amino acids from the C-terminal region of human FGD6
Isotype Ig
Specificity This antibody reacts to FGD6.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name FGD6 (FGD6 Antibody Abstract)
Background Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.Synonyms: FYVE, KIAA1362, RhoGEF and PH domain-containing protein 6, ZFYVE24, Zinc finger FYVE domain-containing protein 24
Molecular Weight 160816 Da
Gene ID 55785
NCBI Accession NP_060821
Research Area Signaling
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-FYVE, RhoGEF and PH Domain Containing 6 (FGD6) (AA 1331-1359), (C-Term) antibody (ABIN952305) FGD6 Antibody (C-term) immunohistochemistry analysis in formalin fixed and para...
Western Blotting (WB) image for anti-FYVE, RhoGEF and PH Domain Containing 6 (FGD6) (AA 1331-1359), (C-Term) antibody (ABIN952305) FGD6 Antibody (C-term) western blot analysis in A549 cell line lysates (35µg/la...
Background publications Barrios-Rodiles, Brown, Ozdamar et al.: "High-throughput mapping of a dynamic signaling network in mammalian cells." in: Science (New York, N.Y.), Vol. 307, Issue 5715, pp. 1621-5, 2005 (PubMed).

Jin, Smith, Stark et al.: "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization." in: Current biology : CB, Vol. 14, Issue 16, pp. 1436-50, 2004 (PubMed).

Catalog No. ABIN952305
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