Galanin Receptor 3 (GALR3) (C-Term), (AA 278-307) antibody

Details for Product No. ABIN952454
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Antigen
Synonyms GALR3, Galnr3
Epitope
C-Term, AA 278-307
(18), (7), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(44), (14), (12), (12)
Host
Rabbit
(38), (6)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
(20), (18), (17), (10), (9), (3), (2), (1), (1)
Pubmed 5 references available
Quantity 0.4 mL
Shipping to United States (Change)
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Catalog No. ABIN952454
357.50 $
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Immunogen KLH conjugated synthetic peptide between 278-307 amino acids from the C-terminal region of human GALR3
Isotype Ig
Specificity This antibody recognizes Human GATLR3 (C-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name GALR3
Background The neuropeptide galanin modulates a variety of physiologic processes including cognition/memory, sensory/pain processing, hormone secretion, and feeding behavior. The human galanin receptors are G protein-coupled receptors that functionally couple to their intracellular effector through distinct signaling pathways. GALR3 is found in many tissues and may be expressed as 1.4-, 2.4-, and 5-kb transcriptsSynonyms: GAL3-R, GALNR3, Galanin receptor type 3
Molecular Weight 39573 Da
Gene ID 8484
NCBI Accession NP_003605
Research Area Neurology
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Berger, Tuechler, Almer et al.: "Elevated expression of galanin receptors in childhood neuroblastic tumors." in: Neuroendocrinology, Vol. 75, Issue 2, pp. 130-8, 2002 (PubMed).

Belfer, Hipp, Bollettino et al.: "Alcoholism is associated with GALR3 but not two other galanin receptor genes." in: Genes, brain, and behavior, Vol. 6, Issue 5, pp. 473-81, 2007 (PubMed).

Gratacòs, Costas, de Cid et al.: "Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 150B, Issue 6, pp. 808-16, 2009 (PubMed).

Saus, Brunet, Armengol et al.: "Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients." in: Journal of psychiatric research, Vol. 44, Issue 14, pp. 971-8, 2010 (PubMed).

Shimada, Miyagawa, Kawashima et al.: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." in: Human genetics, Vol. 128, Issue 4, pp. 433-41, 2010 (PubMed).

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