Glucagon-Like Peptide 2 Receptor (GLP2R) (AA 219-248), (Middle Region) antibody

Details for Product No. ABIN952529
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Synonyms GLP1, GLP2, GRPP, 9530092J08Rik, GLP-2
AA 219-248, Middle Region
(15), (12), (9), (8), (4), (4), (2), (1), (1), (1), (1), (1)
(69), (3), (2), (2), (1)
(64), (7)
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(46), (25), (17), (10), (8), (5), (4), (3), (2), (2), (1), (1), (1)
Pubmed 2 references available
Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 219-248 amino acids from the Central region of human GLP2R
Isotype Ig
Specificity This antibody recognizes Human GLP2R (Center).
Purification Protein A column, followed by peptide affinity purification
Alternative Name GLP2 Receptor (GLP2R Antibody Abstract)
Background The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R). [provided by RefSeq].Synonyms: GLP-2-R, GLP-2R, GLP2R, Glucagon-like peptide 2 receptor
Molecular Weight 63001 Da
Gene ID 9340
NCBI Accession NP_004237
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Glucagon-Like Peptide 2 Receptor (GLP2R) (AA 219-248), (Middle Region) antibody (ABIN952529) Western blot analysis of GLP2R Antibody (Center) Cat.-No AP51856PU-N in A549 cell lin...
Background publications Bailey, Xie, Do et al.: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, 2010 (PubMed).

Pinheiro, Bulik, Thornton et al.: "Association study of 182 candidate genes in anorexia nervosa." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 5, pp. 1070-80, 2010 (PubMed).

Catalog No. ABIN952529
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