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Gonadotropin-Releasing Hormone 2 (GnRH2) (AA 32-62), (Middle Region) antibody

Details for Product No. ABIN952570, Supplier: Log in to see
Antigen
  • GnRH-II
  • cGnRH-II
  • GnRHII
  • gnrh2
  • LH-RHII
  • Gn-RHII
Epitope
AA 32-62, Middle Region
13
10
8
8
4
1
1
Reactivity
Human
38
2
Host
Rabbit
37
1
Clonality
Polyclonal
Conjugate
Un-conjugated
4
4
4
2
2
2
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Western Blotting (WB)
23
17
10
6
3
Supplier
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Immunogen KLH conjugated synthetic peptide between 32~62 amino acids from the Central region of human GNRH2 / Progonadoliberin-2
Isotype Ig
Specificity This antibody recognizes Human GNRH2 / Progonadoliberin-2 (Center).
Purification Protein A column, followed by peptide affinity purification
Alternative Name GNRH2 / Progonadoliberin-2 (GnRH2 Antibody Abstract)
Background The protein encoded by this gene is a preproprotein that is cleaved to form a secreted 10 aa peptide hormone. The secreted decapeptide regulates reproduction in females by stimulating the secretion of both luteinizing- and follicle-stimulating hormones.
Molecular Weight 12918 Da
Gene ID 2797
NCBI Accession NP_001492
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-Gonadotropin-Releasing Hormone 2 (GnRH2) (AA 32-62), (Middle Region) antibody (ABIN952570) Flow cytometric analysis of MDA-MB435 cells using GNRH2 Antibody (Center) Cat.-No AP5...
Western Blotting (WB) image for anti-Gonadotropin-Releasing Hormone 2 (GnRH2) (AA 32-62), (Middle Region) antibody (ABIN952570) Western blot analysis of GNRH2 Antibody (Center) in MDA-MB435 cell line lysates (35ug...
Background publications Poon, Hammond, Leung: "Epidermal growth factor-induced GnRH-II synthesis contributes to ovarian cancer cell invasion." in: Molecular endocrinology (Baltimore, Md.), Vol. 23, Issue 10, pp. 1646-56, 2009 (PubMed).

Yerges, Klei, Cauley et al.: "High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 24, Issue 12, pp. 2039-49, 2009 (PubMed).

Gratacòs, Costas, de Cid et al.: "Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 150B, Issue 6, pp. 808-16, 2009 (PubMed).

Palmieri, Wilson, Iversen et al.: "Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women. ..." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 17, Issue 12, pp. 3567-72, 2008 (PubMed).

Poon, An, So et al.: "Temporal recruitment of transcription factors at the 3',5'-cyclic adenosine 5'-monophosphate-response element of the human GnRH-II promoter." in: Endocrinology, Vol. 149, Issue 10, pp. 5162-71, 2008 (PubMed).