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Details for Product No. ABIN952636

Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9) (AA 280-309), (Middle Region) antibody

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Antigen
Synonyms
csa, grp-75, grp75, hspa9, hspa9b, mortalin, mot, mot2, pbp74, Hspa9a, HSPA9B, CSA, GRP-75, GRP75, MOT, MOT2, MTHSP75, PBP74, 74kDa, Csa, Grp75, Hsc74, Hsp74, Hsp74a, Mortalin, Mot-2, Mot2, Mthsp70, P ... show more
Epitope
»Alternatives AA 280-309, Middle Region
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN952636
Quantity 0.4 mL
Price
346.50 $   Plus shipping costs $45.00
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Product details

Target Details Application Details Handling References Alternatives back to top
Immunogen KLH conjugated synthetic peptide between 280-309 amino acids from the Central region of human Grp75 / HSPA9
Specificity This antibody recognizes Human Grp75 / HSPA9B (Center).
Purification Protein A column, followed by peptide affinity purification

Target Details

Application Details Handling References Alternatives back to top
Alternative Name Grp75 / HSPA9
Background This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2.
Alternate names: 75 kDa glucose-regulated protein, HSPA9B, Heat shock 70 kDa protein 9, MOT, Mortalin, PBP74, Peptide-binding protein 74, Stress-70 protein
Molecular Weight 73680 Da
Gene ID 3313
NCBI Accession NP_004125

Application Details

Target Details Handling References Alternatives back to top
Restrictions For Research Use only

Handling

Target Details Application Details References Alternatives back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months

References

Target Details Application Details Handling Alternatives back to top
Background publications Rikova, Guo, Zeng et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).

Luo, Dizin, Yoon et al.: "Kinetic and structural characterization of human mortalin." in: Protein expression and purification, Vol. 72, Issue 1, pp. 75-81, 2010 (PubMed).

Iosefson, Azem: "Reconstitution of the mitochondrial Hsp70 (mortalin)-p53 interaction using purified proteins--identification of additional interacting regions." in: FEBS letters, Vol. 584, Issue 6, pp. 1080-4, 2010 (PubMed).

Li, Xu, Ling et al.: "mot-2-Mediated cross talk between nuclear factor-B and p53 is involved in arsenite-induced tumorigenesis of human embryo lung fibroblast cells." in: Environmental health perspectives, Vol. 118, Issue 7, pp. 936-42, 2010 (PubMed).

Goswami, Chittoor, DSilva: "Understanding the functional interplay between mammalian mitochondrial Hsp70 chaperone machine components." in: The Journal of biological chemistry, Vol. 285, Issue 25, pp. 19472-82, 2010 (PubMed).

Alternatives

Target Details Application Details Handling References back to top
Alternatives for antigen "Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9)", type "Antibodies"
Hosts (57), (21)
Reactivities (74), (43), (42), (15), (12), (12), (2), (1), (1), (1)
Applications (59), (25), (23), (15), (15), (14), (10), (5), (4), (3), (2), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (9), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
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