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Holocytochrome C Synthase (HCCS) (AA 179-209), (Middle Region) antibody

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Synonyms hccsb, id:ibd1278, wu:fb18h01, wu:fc64e12, wu:fi43e01, cchl, mcops7, DDBDRAFT_0217711, DDBDRAFT_0266707, DDB_0217711, DDB_0266707, CCHL, MCOPS7, RGD1563855
AA 179-209, Middle Region
(15), (10), (10), (7), (3), (3), (3), (3), (2), (1), (1), (1)
Human, Mouse (Murine)
(76), (31), (22), (3)
(66), (11)
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(57), (31), (29), (11), (10), (7), (6), (3), (3), (1)
Pubmed 3 references available
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Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 179~209 amino acids from the Central region of human HCCS / CCHL
Isotype Ig
Specificity This antibody recognizes Human and Mouse HCCS / CCHL (Center).
Purification Protein A column, followed by peptide affinity purification
Alternative Name HCCS / CCHL (HCCS Antibody Abstract)
Background The protein encoded by this gene is an enzyme that covalently links a heme group to the apoprotein of cytochrome c. Defects in this gene are a cause of microphthalmia syndromic type 7 (MCOPS7). Three transcript variants encoding the same protein have been found for this gene.Synonyms: Cytochrome c-type heme lyase, Holocytochrome c-type synthase
Molecular Weight 30602 Da
Gene ID 3052
NCBI Accession NP_001116080
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Holocytochrome C Synthase (HCCS) (AA 179-209), (Middle Region) antibody (ABIN952686) Immunohistochemistry analysis in formalin fixed and paraffin embedded colon carcinoma...
Western Blotting (WB) image for anti-Holocytochrome C Synthase (HCCS) (AA 179-209), (Middle Region) antibody (ABIN952686) Western blot analysis of HCCS / CCHL Antibody (Center) in mouse heart tissue lysates ...
Western Blotting (WB) image for anti-Holocytochrome C Synthase (HCCS) (AA 179-209), (Middle Region) antibody (ABIN952686) Western blot analysis of HCCS / CCHL Antibody (Center) in WiDr cell line lysates (35u...
Background publications Need, Attix, McEvoy et al.: "A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB." in: Human molecular genetics, Vol. 18, Issue 23, pp. 4650-61, 2009 (PubMed).

Nakashima-Kamimura, Asoh, Ishibashi et al.: "MIDAS/GPP34, a nuclear gene product, regulates total mitochondrial mass in response to mitochondrial dysfunction." in: Journal of cell science, Vol. 118, Issue Pt 22, pp. 5357-67, 2005 (PubMed).

Prakash, Cormier, McCall et al.: "Loss of holocytochrome c-type synthetase causes the male lethality of X-linked dominant microphthalmia with linear skin defects (MLS) syndrome." in: Human molecular genetics, Vol. 11, Issue 25, pp. 3237-48, 2002 (PubMed).

Catalog No. ABIN952686
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