Holocytochrome C Synthase (HCCS) (AA 179-209), (Middle Region) antibody

Details for Product No. ABIN952686
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Antigen
Synonyms hccsb, id:ibd1278, wu:fb18h01, wu:fc64e12, wu:fi43e01, cchl, mcops7, DDBDRAFT_0217711, DDBDRAFT_0266707, DDB_0217711, DDB_0266707, CCHL, MCOPS7, RGD1563855
Epitope
AA 179-209, Middle Region
(7), (3), (3), (3), (3), (2), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(48), (26), (15), (12), (1)
Host
Rabbit
(42), (7)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(38), (20), (19), (10), (9), (6), (4), (3), (2), (1)
Pubmed 3 references available
Quantity 0.4 mL
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Catalog No. ABIN952686
357.50 $
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Immunogen KLH conjugated synthetic peptide between 179~209 amino acids from the Central region of human HCCS / CCHL
Specificity This antibody recognizes Human and Mouse HCCS / CCHL (Center).
Purification Protein A column, followed by peptide affinity purification
Alternative Name HCCS / CCHL
Background The protein encoded by this gene is an enzyme that covalently links a heme group to the apoprotein of cytochrome c. Defects in this gene are a cause of microphthalmia syndromic type 7 (MCOPS7). Three transcript variants encoding the same protein have been found for this gene.
Alternate names: Cytochrome c-type heme lyase, Holocytochrome c-type synthase
Molecular Weight 30602 Da
Gene ID 3052
NCBI Accession NP_001116080
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Prakash, Cormier, McCall et al.: "Loss of holocytochrome c-type synthetase causes the male lethality of X-linked dominant microphthalmia with linear skin defects (MLS) syndrome." in: Human molecular genetics, Vol. 11, Issue 25, pp. 3237-48, 2002 (PubMed).

Nakashima-Kamimura, Asoh, Ishibashi et al.: "MIDAS/GPP34, a nuclear gene product, regulates total mitochondrial mass in response to mitochondrial dysfunction." in: Journal of cell science, Vol. 118, Issue Pt 22, pp. 5357-67, 2005 (PubMed).

Need, Attix, McEvoy et al.: "A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB." in: Human molecular genetics, Vol. 18, Issue 23, pp. 4650-61, 2009 (PubMed).

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