Histone Deacetylase 11 (HDAC11) (AA 196-226), (Middle Region) antibody

Details for Product No. ABIN952697
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Antigen
Synonyms HD11, CG31119, DHDACX, Dmel\\CG31119, HDAC11, HDACX, dHDAC11, dmHDA403, zgc:91942
Epitope
AA 196-226, Middle Region
(11), (11), (8), (7), (7), (3), (2), (2), (1)
Reactivity
Human, Mouse (Murine)
(63), (28), (18), (12), (12), (1), (1), (1)
Host
Rabbit
(61), (10)
Clonality
Polyclonal
Conjugate
Un-conjugated
(5), (5), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(61), (38), (18), (10), (9), (7), (3), (3), (2), (1)
Pubmed 5 references available
Catalog no. ABIN952697
Quantity 0.4 mL
Price
357.50 $   Plus shipping costs $45.00
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen KLH conjugated synthetic peptide between 196-226 amino acids from the Central region of human HDAC11
Specificity This antibody recognizes Human and Mouse HDAC11 (Center).
Purification Protein A column, followed by peptide affinity purification
Alternative Name HDAC11
Background This gene encodes a class IV histone deacetylase. The encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants.
Alternate names: HD11, Histone deacetylase 11
Molecular Weight 39183 Da
Gene ID 79885
NCBI Accession NP_079103
Research Area Chromatin and Nuclear Signaling, Wnt, DNA/RNA, Transcription Factors
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Fournel, Bonfils, Hou et al.: "MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity in vitro and in vivo." in: Molecular cancer therapeutics, Vol. 7, Issue 4, pp. 759-68, 2008 (PubMed).

Villagra, Cheng, Wang et al.: "The histone deacetylase HDAC11 regulates the expression of interleukin 10 and immune tolerance." in: Nature immunology, Vol. 10, Issue 1, pp. 92-100, 2008 (PubMed).

Georgopoulos: "From immunity to tolerance through HDAC." in: Nature immunology, Vol. 10, Issue 1, pp. 13-4, 2008 (PubMed).

Glozak, Seto: "Acetylation/deacetylation modulates the stability of DNA replication licensing factor Cdt1." in: The Journal of biological chemistry, Vol. 284, Issue 17, pp. 11446-53, 2009 (PubMed).

Janssen, Schmalbach, Boeselt et al.: "Differential histone deacetylase mRNA expression patterns in amyotrophic lateral sclerosis." in: Journal of neuropathology and experimental neurology, Vol. 69, Issue 6, pp. 573-81, 2010 (PubMed).

Hosts (61), (10)
Reactivities (63), (28), (18), (12), (12), (1), (1), (1)
Applications (61), (38), (18), (10), (9), (7), (3), (3), (2), (1)
Conjugates (5), (5), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (11), (11), (8), (7), (7), (3), (2), (2), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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