Homeobox B6 (HOXB6) (AA 135-163), (Middle Region) antibody

Details for Product No. ABIN952778
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Synonyms ZF-22, ZF22, hox-2.2, hox-B6, hoxb6, z-39, HOXB6, MGC154540, hox2, hu-2, hox2b, RGD1562142, HOX2, HOX2B, HU-2, Hox-2.2
AA 135-163, Middle Region
(18), (15), (14), (14), (2), (2), (2), (1), (1)
Human, Mouse (Murine)
(46), (27), (13), (1), (1)
(49), (9), (2)
(6), (6), (6), (5), (5), (5), (1), (1), (1), (1), (1), (1), (1), (1)
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Paraffin-embedded Sections) (IHC (frpe)), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(51), (31), (16), (10), (6), (5)
Pubmed 4 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
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Catalog No. ABIN952778
357.50 $
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Immunogen KLH conjugated synthetic peptide between 135-163 amino acids from the Central region of human HOXB6 / HOX2B
Isotype Ig
Specificity This antibody recognizes Human and Mouse HOXB6 / HOX2B (Center). Other species not tested.
Purification Protein A column, followed by peptide affinity purification
Alternative Name HOXB6 / HOX2B
Background This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer.Synonyms: HU-2, Homeobox protein Hox-B6, Hox-2.2, Hox-2B
Molecular Weight 25432 Da
Gene ID 3216
NCBI Accession NP_061825
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Ferrai, Naum-Onganía, Longobardi et al.: "Induction of HoxB transcription by retinoic acid requires actin polymerization." in: Molecular biology of the cell, Vol. 20, Issue 15, pp. 3543-51, 2009 (PubMed).

Matsuoka, Ballif, Smogorzewska et al.: "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." in: Science (New York, N.Y.), Vol. 316, Issue 5828, pp. 1160-6, 2007 (PubMed).

Lamesch, Li, Milstein et al.: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, 2007 (PubMed).

Chen, Li, Xu et al.: "Mutation screening of BMP4, BMP7, HOXA4 and HOXB6 genes in Chinese patients with hypospadias." in: European journal of human genetics : EJHG, Vol. 15, Issue 1, pp. 23-8, 2006 (PubMed).

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