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Homeobox B6 (HOXB6) (AA 135-163), (Middle Region) antibody

Details for Product No. ABIN952778, Supplier: Log in to see
Antigen
  • ZF-22
  • ZF22
  • hox-2.2
  • hox-B6
  • hoxb6
  • z-39
  • HOXB6
  • MGC154540
  • hox2
  • hu-2
  • hox2b
  • RGD1562142
  • HOX2
  • HOX2B
  • HU-2
  • Hox-2.2
Epitope
AA 135-163, Middle Region
19
15
15
15
11
2
2
1
1
1
Reactivity
Human, Mouse (Murine)
39
18
3
1
1
Host
Rabbit
43
9
2
Clonality
Polyclonal
Conjugate
Un-conjugated
5
5
5
5
5
5
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
49
40
15
4
2
Supplier
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Immunogen KLH conjugated synthetic peptide between 135-163 amino acids from the Central region of human HOXB6 / HOX2B
Isotype Ig
Specificity This antibody recognizes Human and Mouse HOXB6 / HOX2B (Center). Other species not tested.
Purification Protein A column, followed by peptide affinity purification
Alternative Name HOXB6 / HOX2B (HOXB6 Antibody Abstract)
Background This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development, including that of lung and skin, and has been localized to both the nucleus and cytoplasm. Altered expression of this gene or a change in the subcellular localization of its protein is associated with some cases of acute myeloid leukemia and colorectal cancer.Synonyms: HU-2, Homeobox protein Hox-B6, Hox-2.2, Hox-2B
Molecular Weight 25432 Da
Gene ID 3216
NCBI Accession NP_061825
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Homeobox B6 (HOXB6) (AA 135-163), (Middle Region) antibody (ABIN952778) Immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil ti...
Western Blotting (WB) image for anti-Homeobox B6 (HOXB6) (AA 135-163), (Middle Region) antibody (ABIN952778) Western blot analysis of HOXB6 / HOX2B Antibody (Center) in mouse kidney tissue lysat...
Background publications Ferrai, Naum-Onganía, Longobardi et al.: "Induction of HoxB transcription by retinoic acid requires actin polymerization." in: Molecular biology of the cell, Vol. 20, Issue 15, pp. 3543-51, 2009 (PubMed).

Matsuoka, Ballif, Smogorzewska et al.: "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." in: Science (New York, N.Y.), Vol. 316, Issue 5828, pp. 1160-6, 2007 (PubMed).

Lamesch, Li, Milstein et al.: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, 2007 (PubMed).

Chen, Li, Xu et al.: "Mutation screening of BMP4, BMP7, HOXA4 and HOXB6 genes in Chinese patients with hypospadias." in: European journal of human genetics : EJHG, Vol. 15, Issue 1, pp. 23-8, 2006 (PubMed).