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Homeobox B9 (HOXB9) (AA 147-176), (Middle Region) antibody

Details for Product No. ABIN952780, Supplier: Log in to see
Antigen
  • BZ-23
  • bz23
  • hoxb9
  • wu:fc06b03
  • hox2
  • hox2e
  • xhoxb9
  • hox-2.5
  • MGC75797
  • HOXB9
  • HOX-2.5
  • HOX2
  • HOX2E
  • Hox-2.5
Epitope
AA 147-176, Middle Region
22
15
10
10
10
8
6
3
3
2
1
1
1
1
1
1
Reactivity
Human
64
18
7
5
3
2
Host
Rabbit
47
16
5
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
65
37
7
7
1
1
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 147-176 amino acids from the Central region of Human HOXB9
Isotype Ig
Specificity This antibody recognizes Human HOXB9 / HOX2E (Center).
Purification Protein A column, followed by peptide affinity purification
Alternative Name HOXB9 / HOX2E (HOXB9 Antibody Abstract)
Background HOXB9 is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer.Synonyms: Homeobox protein Hox-B9, Hox-2.5, Hox-2E
Molecular Weight 28059 Da
Gene ID 3219
NCBI Accession NP_076922
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Homeobox B9 (HOXB9) (AA 147-176), (Middle Region) antibody (ABIN952780) Western blot analysis of HOXB9 / HOX2E Antibody (Center) in HL-60 cell line lysates (...
Background publications Hayashida, Takahashi, Chiba et al.: "HOXB9, a gene overexpressed in breast cancer, promotes tumorigenicity and lung metastasis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 3, pp. 1100-5, 2010 (PubMed).

Need, Attix, McEvoy et al.: "A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB." in: Human molecular genetics, Vol. 18, Issue 23, pp. 4650-61, 2009 (PubMed).

Nguyen, Chiang, Zhang et al.: "WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis." in: Cell, Vol. 138, Issue 1, pp. 51-62, 2009 (PubMed).

Rouault, Scotet, Autret et al.: "Do HOXB9 and COL1A1 genes play a role in congenital dislocation of the hip? Study in a Caucasian population." in: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 17, Issue 8, pp. 1099-105, 2009 (PubMed).

Venkatesan, Rual, Vazquez et al.: "An empirical framework for binary interactome mapping...." in: Nature methods, Vol. 6, Issue 1, pp. 83-90, 2008 (PubMed).