Homeobox B9 (HOXB9) (AA 147-176), (Middle Region) antibody

Details for Product No. ABIN952780
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Antigen
Synonyms BZ-23, bz23, hoxb9, wu:fc06b03, hox2, hox2e, xhoxb9, hox-2.5, MGC75797, HOXB9, HOX-2.5, HOX2, HOX2E, Hox-2.5
Epitope
AA 147-176, Middle Region
(15), (10), (7), (5), (4), (4), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(60), (18), (4), (2), (1)
Host
Rabbit
(42), (19), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
(60), (37), (8), (4), (4), (2), (1), (1)
Pubmed 5 references available
Quantity 0.4 mL
Shipping to United States (Change)
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Catalog No. ABIN952780
357.50 $
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Immunogen KLH conjugated synthetic peptide between 147-176 amino acids from the Central region of Human HOXB9
Isotype Ig
Specificity This antibody recognizes Human HOXB9 / HOX2E (Center).
Purification Protein A column, followed by peptide affinity purification
Alternative Name HOXB9 / HOX2E
Background HOXB9 is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer.Synonyms: Homeobox protein Hox-B9, Hox-2.5, Hox-2E
Molecular Weight 28059 Da
Gene ID 3219
NCBI Accession NP_076922
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Venkatesan, Rual, Vazquez et al.: "An empirical framework for binary interactome mapping...." in: Nature methods, Vol. 6, Issue 1, pp. 83-90, 2008 (PubMed).

Rouault, Scotet, Autret et al.: "Do HOXB9 and COL1A1 genes play a role in congenital dislocation of the hip? Study in a Caucasian population." in: Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society, Vol. 17, Issue 8, pp. 1099-105, 2009 (PubMed).

Nguyen, Chiang, Zhang et al.: "WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis." in: Cell, Vol. 138, Issue 1, pp. 51-62, 2009 (PubMed).

Need, Attix, McEvoy et al.: "A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB." in: Human molecular genetics, Vol. 18, Issue 23, pp. 4650-61, 2009 (PubMed).

Hayashida, Takahashi, Chiba et al.: "HOXB9, a gene overexpressed in breast cancer, promotes tumorigenicity and lung metastasis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 3, pp. 1100-5, 2010 (PubMed).

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