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Ligand of Numb-Protein X 2 (LNX2) (AA 550-579), (C-Term) antibody

Details for Product No. ABIN953200, Supplier: Login to see
Antigen
  • LNX2
  • lnx2
  • MGC146476
  • PDZRN1
  • 9630046H24
  • AW209022
Epitope
AA 550-579, C-Term
17
15
3
3
3
2
1
1
Reactivity
Human
35
1
1
Host
Rabbit
28
7
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
32
22
15
2
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 550-579 amino acids from the C-terminal region of human LNX2
Isotype Ig
Specificity This antibody recognizes Human LNX2 (C-term).
Purification Protein A column, followed by peptide affinity purification
Alternative Name LNX2
Background LNX2 (Ligand of numb-protein X 2) is a multimodular protein that binds to NUMB via the NPXY motif. It may serve as a molecular scaffold that localizes unrelated, interacting proteins, such as NUMB, to specific subcellular sites.Synonyms: LNX2, Ligand of Numb protein X 2, Numb-binding protein 2, PDZ domain-containing RING finger protein 1, PDZRN1
Molecular Weight 76004 Da
Gene ID 222484
NCBI Accession NP_699202
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Ligand of Numb-Protein X 2 (LNX2) (AA 550-579), (C-Term) antibody (ABIN953200) Immunohistochemistry analysis in formalin fixed and paraffin embedded human rectum ti...
Western Blotting (WB) image for anti-Ligand of Numb-Protein X 2 (LNX2) (AA 550-579), (C-Term) antibody (ABIN953200) Western blot analysis of LNX2 Antibody (C-term) in HepG2, 293, NCI-H460 cell line lys...
Background publications Thorleifsson, Walters, Gudbjartsson et al.: "Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity...." in: Nature genetics, Vol. 41, Issue 1, pp. 18-24, 2008 (PubMed).

Sullivan, Lin, Tzeng et al.: "Genomewide association for schizophrenia in the CATIE study: results of stage 1." in: Molecular psychiatry, Vol. 13, Issue 6, pp. 570-84, 2008 (PubMed).

Dunham, Matthews, Burton et al.: "The DNA sequence and analysis of human chromosome 13. ..." in: Nature, Vol. 428, Issue 6982, pp. 522-8, 2004 (PubMed).

Rice, Northcutt, Kurschner: "The Lnx family proteins function as molecular scaffolds for Numb family proteins." in: Molecular and cellular neurosciences, Vol. 18, Issue 5, pp. 525-40, 2002 (PubMed).