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Membrane Protein, Palmitoylated 6 (MAGUK P55 Subfamily Member 6) (MPP6) (AA 367-396), (Middle Region) antibody

Details for Product No. ABIN953287, Supplier: Log in to see
Antigen
  • mpp6
  • MGC55662
  • zgc:55662
  • PALS2
  • VAM-1
  • VAM1
  • p55T
  • P55t
  • Pals2
Epitope
AA 367-396, Middle Region
19
3
2
2
2
2
2
1
1
1
Reactivity
Human, Mouse (Murine)
40
17
13
4
4
4
2
2
2
2
Host
Rabbit
19
19
3
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Western Blotting (WB)
36
21
9
4
3
2
2
1
1
1
1
Supplier
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Immunogen Synthetic peptide - KLH conjugated - corresponding to the central region (between 367-396aa) of human MPP6 / MAGUK p55 subfamily member 6
Isotype Ig
Specificity This antibody recognizes MPP6 / MAGUK p55 subfamily member 6.
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse
Purification Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Alternative Name MPP6 (MPP6 Antibody Abstract)
Background MPP6 is a member of the p55-like MAGUK subfamily. Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies - DLG-like, ZO1-like , p55-like and LIN2-like - based on their size and the presence of additional domains [Tseng et al., 2001, PubMed 11311936].Synonyms: MAGUK p55 subfamily member 6, VAM1, Veli-associated MAGUK 1
Gene ID 51678
NCBI Accession NP_057531
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-Membrane Protein, Palmitoylated 6 (MAGUK P55 Subfamily Member 6) (MPP6) (AA 367-396), (Middle Region) antibody (ABIN953287) Flow cytometric analysis of 293 cells (right histogram) compared to a negative contro...
Western Blotting (WB) image for anti-Membrane Protein, Palmitoylated 6 (MAGUK P55 Subfamily Member 6) (MPP6) (AA 367-396), (Middle Region) antibody (ABIN953287) Western blot analysis of MPP6 (arrow) in mouse cerebellum tissue lysates (35ug/lane) ...
Background publications Scheel, Hermann, Ohrndorf et al.: "Prospective 7 year follow up imaging study comparing radiography, ultrasonography, and magnetic resonance imaging in rheumatoid arthritis finger joints." in: Annals of the rheumatic diseases, Vol. 65, Issue 5, pp. 595-600, 2006 (PubMed).

Rush, Moritz, Lee et al.: "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells." in: Nature biotechnology, Vol. 23, Issue 1, pp. 94-101, 2005 (PubMed).

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