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Membrane Protein, Palmitoylated 6 (MAGUK P55 Subfamily Member 6) (MPP6) (AA 367-396), (Middle Region) antibody

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Antigen
Synonyms mpp6, MGC55662, zgc:55662, PALS2, VAM-1, VAM1, p55T, P55t, Pals2
Epitope
AA 367-396, Middle Region
(19), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(43), (17), (13), (4), (4), (4), (2), (2), (2), (2)
Host
Rabbit
(21), (20), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1)
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Western Blotting (WB)
(39), (22), (10), (4), (3), (2), (2), (1), (1), (1), (1)
Pubmed 2 references available
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Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen Synthetic peptide - KLH conjugated - corresponding to the central region (between 367-396aa) of human MPP6 / MAGUK p55 subfamily member 6
Isotype Ig
Specificity This antibody recognizes MPP6 / MAGUK p55 subfamily member 6.
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse
Purification Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Alternative Name MPP6 (MPP6 Antibody Abstract)
Background MPP6 is a member of the p55-like MAGUK subfamily. Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies - DLG-like, ZO1-like , p55-like and LIN2-like - based on their size and the presence of additional domains [Tseng et al., 2001, PubMed 11311936].Synonyms: MAGUK p55 subfamily member 6, VAM1, Veli-associated MAGUK 1
Gene ID 51678
NCBI Accession NP_057531
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Flow Cytometry (FACS) image for anti-Membrane Protein, Palmitoylated 6 (MAGUK P55 Subfamily Member 6) (MPP6) (AA 367-396), (Middle Region) antibody (ABIN953287) Flow cytometric analysis of 293 cells (right histogram) compared to a negative contro...
Western Blotting (WB) image for anti-Membrane Protein, Palmitoylated 6 (MAGUK P55 Subfamily Member 6) (MPP6) (AA 367-396), (Middle Region) antibody (ABIN953287) Western blot analysis of MPP6 (arrow) in mouse cerebellum tissue lysates (35ug/lane) ...
Background publications Scheel, Hermann, Ohrndorf et al.: "Prospective 7 year follow up imaging study comparing radiography, ultrasonography, and magnetic resonance imaging in rheumatoid arthritis finger joints." in: Annals of the rheumatic diseases, Vol. 65, Issue 5, pp. 595-600, 2006 (PubMed).

Rush, Moritz, Lee et al.: "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells." in: Nature biotechnology, Vol. 23, Issue 1, pp. 94-101, 2005 (PubMed).

Catalog No. ABIN953287
$401.50
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