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Matrix Extracellular phosphoglycoprotein (MEPE) (AA 26-56), (N-Term) antibody

Details for Product No. ABIN953388, Supplier: Login to see
Antigen
  • OF45
  • OC-116
  • Of45
Epitope
N-Term, AA 26-56
16
14
5
3
2
2
1
1
Reactivity
Human
42
5
1
Host
Rabbit
47
1
Clonality
Polyclonal
Conjugate
Un-conjugated
4
4
3
2
2
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
31
22
11
5
3
2
1
1
Supplier
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Immunogen KLH conjugated synthetic peptide between 26-56 amino acids from the N-terminal region of human MEPE
Isotype Ig
Specificity This antibody reacts to MEPE.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name MEPE / OF45 (MEPE Antibody Abstract)
Background MEPE seems to play a role in mineralization.Synonyms: Matrix extracellular phosphoglycoprotein, Osteoblast/osteocyte factor 45
Molecular Weight 58419 Da
Gene ID 56955
NCBI Accession NP_001171623
Pathways
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Matrix Extracellular phosphoglycoprotein (MEPE) (AA 26-56), (N-Term) antibody (ABIN953388) MEPE Antibody (N-term) western blot analysis in NCI-H460 cell line lysates (35µg/lane...
Background publications Boskey, Chiang, Fermanis et al.: "MEPE's diverse effects on mineralization." in: Calcified tissue international, Vol. 86, Issue 1, pp. 42-6, 2010 (PubMed).

Rivadeneira, Styrkársdottir, Estrada et al.: "Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies." in: Nature genetics, Vol. 41, Issue 11, pp. 1199-206, 2009 (PubMed).

Pereira, Juppner, Azucena-Serrano et al.: "Patterns of FGF-23, DMP1, and MEPE expression in patients with chronic kidney disease." in: Bone, Vol. 45, Issue 6, pp. 1161-8, 2009 (PubMed).

Yerges, Klei, Cauley et al.: "High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 24, Issue 12, pp. 2039-49, 2009 (PubMed).

Marks, Churchill, Debnam et al.: "Matrix extracellular phosphoglycoprotein inhibits phosphate transport." in: Journal of the American Society of Nephrology : JASN, Vol. 19, Issue 12, pp. 2313-20, 2008 (PubMed).