Methyltransferase Like 1 (METTL1) (AA 154-183), (Middle Region) antibody

Details for Product No. ABIN953396
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms Dmel\\CG4045, EG:22E5.4, C12orf1, TRM8, TRMT8, YDL201w, 2810012D02Rik
Epitope
AA 154-183, Middle Region
(8), (7), (4), (2), (2), (1), (1), (1)
Reactivity
Human
(23), (6), (6), (1)
Host
Rabbit
(20), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(19), (13), (3), (2), (1)
Pubmed 4 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN953396
357.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen KLH conjugated synthetic peptide between 154~183 amino acids from the Central region of human METTL1
Specificity This antibody reacts to METTL1.
Purification Affinity chromatography on Protein A
Alternative Name METTL1
Background This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation.
Alternate names: C12orf1, Methyltransferase-like protein 1, tRNA (guanine-N(7)-)-methyltransferase, tRNA(m7G46)-methyltransferas
Gene ID 4234
NCBI Accession NP_005362
Research Area Chromatin and Nuclear Signaling, DNA/RNA
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% (w/v) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Alexandrov, Martzen, Phizicky: "Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA." in: RNA (New York, N.Y.), Vol. 8, Issue 10, pp. 1253-66, 2002 (PubMed).

Cartlidge, Knebel, Peggie et al.: "The tRNA methylase METTL1 is phosphorylated and inactivated by PKB and RSK in vitro and in cells." in: The EMBO journal, Vol. 24, Issue 9, pp. 1696-705, 2005 (PubMed).

"Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20." in: Nature genetics, Vol. 41, Issue 7, pp. 824-8, 2009 (PubMed).

Guey, García-Closas, Murta-Nascimento et al.: "Genetic susceptibility to distinct bladder cancer subphenotypes." in: European urology, Vol. 57, Issue 2, pp. 283-92, 2010 (PubMed).

Validation Images
Did you look for something else?
back to top