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Methyltransferase Like 1 (METTL1) (AA 154-183), (Middle Region) antibody

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Synonyms Dmel\\CG4045, EG:22E5.4, C12orf1, TRM8, TRMT8, YDL201w, 2810012D02Rik
AA 154-183, Middle Region
(15), (15), (10), (2), (2), (2), (1), (1), (1), (1), (1)
(39), (9), (9), (1)
(37), (2)
(2), (2), (2), (2), (2), (2)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(35), (24), (6), (2), (1)
Pubmed 4 references available
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Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 154~183 amino acids from the Central region of human METTL1
Isotype Ig
Specificity This antibody reacts to METTL1.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Affinity chromatography on Protein A
Alternative Name METTL1 (METTL1 Antibody Abstract)
Background This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation.Synonyms: C12orf1, Methyltransferase-like protein 1, tRNA (guanine-N(7)-)-methyltransferase, tRNA(m7G46)-methyltransferas
Molecular Weight 31471 Da
Gene ID 4234
NCBI Accession NP_005362
Research Area Chromatin and Nuclear Signaling, DNA/RNA
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS, 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Methyltransferase Like 1 (METTL1) (AA 154-183), (Middle Region) antibody (ABIN953396) Western blot analysis of METTL1 Antibody (Center) in Ramos cell line lysates (35µg/la...
Background publications Guey, García-Closas, Murta-Nascimento et al.: "Genetic susceptibility to distinct bladder cancer subphenotypes." in: European urology, Vol. 57, Issue 2, pp. 283-92, 2010 (PubMed).

"Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20." in: Nature genetics, Vol. 41, Issue 7, pp. 824-8, 2009 (PubMed).

Cartlidge, Knebel, Peggie et al.: "The tRNA methylase METTL1 is phosphorylated and inactivated by PKB and RSK in vitro and in cells." in: The EMBO journal, Vol. 24, Issue 9, pp. 1696-705, 2005 (PubMed).

Alexandrov, Martzen, Phizicky: "Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA." in: RNA (New York, N.Y.), Vol. 8, Issue 10, pp. 1253-66, 2002 (PubMed).

Catalog No. ABIN953396
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