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Details for Product No. ABIN953408

Mannosyl (Beta-1,4-)-Glycoprotein beta-1,4-N-Acetylglucosaminyltransferase (MGAT3) (C-Term), (AA 425-454) antibody

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Antigen
Synonyms GnT-III, AI848272, 1110038J12Rik, GNT-III, GNT3, MGAT3, mgat3, zgc:112067
Epitope
»Alternatives C-Term, AA 425-454
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN953408
Quantity 0.4 mL
Price
346.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide between 425-454 amino acids from the C-terminal region of human MGAT3
Specificity This antibody reacts to MGAT3.
Purification Affinity chromatography on Protein A
Alternative Name MGAT3
Background There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. The enzyme encoded by this gene transfers a GlcNAc residue to the beta-linked mannose of the trimannosyl core of N-linked oligosaccharides and produces a bisecting GlcNAc. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alternate names: 4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase, Beta-1, GGNT3
Gene ID 4248
NCBI Accession NP_001091740
Research Area Organelles
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% (w/v) sodium azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Fiala, Liu, Espinosa-Jeffrey et al.: "Innate immunity and transcription of MGAT-III and Toll-like receptors in Alzheimer's disease patients are improved by bisdemethoxycurcumin." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 31, pp. 12849-54, 2007 (PubMed).

Sato, Isaji, Tajiri et al.: "An N-glycosylation site on the beta-propeller domain of the integrin alpha5 subunit plays key roles in both its function and site-specific modification by beta1,4-N-acetylglucosaminyltransferase III." in: The Journal of biological chemistry, Vol. 284, Issue 18, pp. 11873-81, 2009 (PubMed).

Pinho, Reis, Paredes et al.: "The role of N-acetylglucosaminyltransferase III and V in the post-transcriptional modifications of E-cadherin." in: Human molecular genetics, Vol. 18, Issue 14, pp. 2599-608, 2009 (PubMed).

Akasaka-Manya, Manya, Sakurai et al.: "Protective effect of N-glycan bisecting GlcNAc residues on beta-amyloid production in Alzheimer's disease." in: Glycobiology, Vol. 20, Issue 1, pp. 99-106, 2009 (PubMed).

Benson, Grobarova, Richter et al.: "Glycosylation regulates NK cell-mediated effector function through PI3K pathway." in: International immunology, Vol. 22, Issue 3, pp. 167-77, 2010 (PubMed).

Alternatives for antigen "Mannosyl (Beta-1,4-)-Glycoprotein beta-1,4-N-Acetylglucosaminyltransferase (MGAT3)", type "Antibodies"
Hosts (13), (3)
Reactivities (16), (5), (2)
Applications (14), (7), (4), (4), (2), (1), (1)
Epitopes (4), (3), (3), (2), (2), (1), (1), (1)
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