Mannosyl (Beta-1,4-)-Glycoprotein beta-1,4-N-Acetylglucosaminyltransferase (MGAT3) (C-Term), (AA 425-454) antibody

Details for Product No. ABIN953408
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Antigen
Synonyms GnT-III, AI848272, 1110038J12Rik, GNT-III, GNT3, MGAT3, mgat3, zgc:112067
Epitope
C-Term, AA 425-454
(4), (2), (2), (2), (2), (1), (1), (1), (1)
Reactivity
Human
(18), (4), (2)
Host
Rabbit
(15), (3)
Clonality
Polyclonal
Application
ELISA, Western Blotting (WB)
(16), (7), (5), (4), (3), (1), (1), (1)
Pubmed 5 references available
Catalog no. ABIN953408
Quantity 0.4 mL
Price
357.50 $   Plus shipping costs $45.00
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days

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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen KLH conjugated synthetic peptide between 425-454 amino acids from the C-terminal region of human MGAT3
Specificity This antibody reacts to MGAT3.
Purification Affinity chromatography on Protein A
Alternative Name MGAT3
Background There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. The enzyme encoded by this gene transfers a GlcNAc residue to the beta-linked mannose of the trimannosyl core of N-linked oligosaccharides and produces a bisecting GlcNAc. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alternate names: 4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase, Beta-1, GGNT3
Gene ID 4248
NCBI Accession NP_001091740
Research Area Organelles
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS 0.09% (w/v) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Fiala, Liu, Espinosa-Jeffrey et al.: "Innate immunity and transcription of MGAT-III and Toll-like receptors in Alzheimer's disease patients are improved by bisdemethoxycurcumin." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 31, pp. 12849-54, 2007 (PubMed).

Sato, Isaji, Tajiri et al.: "An N-glycosylation site on the beta-propeller domain of the integrin alpha5 subunit plays key roles in both its function and site-specific modification by beta1,4-N-acetylglucosaminyltransferase III." in: The Journal of biological chemistry, Vol. 284, Issue 18, pp. 11873-81, 2009 (PubMed).

Pinho, Reis, Paredes et al.: "The role of N-acetylglucosaminyltransferase III and V in the post-transcriptional modifications of E-cadherin." in: Human molecular genetics, Vol. 18, Issue 14, pp. 2599-608, 2009 (PubMed).

Akasaka-Manya, Manya, Sakurai et al.: "Protective effect of N-glycan bisecting GlcNAc residues on beta-amyloid production in Alzheimer's disease." in: Glycobiology, Vol. 20, Issue 1, pp. 99-106, 2009 (PubMed).

Benson, Grobarova, Richter et al.: "Glycosylation regulates NK cell-mediated effector function through PI3K pathway." in: International immunology, Vol. 22, Issue 3, pp. 167-77, 2010 (PubMed).

Hosts (15), (3)
Reactivities (18), (4), (2)
Applications (16), (7), (5), (4), (3), (1), (1), (1)
Epitopes (4), (2), (2), (2), (2), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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