Metastasis Associated 1 Family, Member 3 (MTA3) (C-Term), (AA 558-587) antibody

Details for Product No. ABIN953531
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Synonyms MTA3, DKFZp468E247, 1110002J22Rik, mKIAA1266
C-Term, AA 558-587
(19), (14), (6), (3), (2), (2), (1), (1), (1), (1)
(45), (5), (5), (2), (2), (2)
(33), (12)
(2), (2), (2), (2), (2), (2)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(35), (20), (6), (5), (3), (3), (2), (2), (1), (1)
Pubmed 5 references available
Quantity 0.4 mL
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Catalog No. ABIN953531
357.50 $
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Immunogen Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 558-587aa) of human MTA3.
Isotype Ig
Specificity This antibody recognizes human MTA3 at C-term.
Purification Purified through a Protein A column followed by peptide affinity purification
Alternative Name MTA3
Background MTA3 plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels.Synonyms: KIAA1266, Metastasis-associated protein MTA3
Molecular Weight 67504 Da
Gene ID 57504
NCBI Accession NP_065795
Research Area Cancer, Transcription Factors
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Brüning, Makovitzky, Gingelmaier et al.: "The metastasis-associated genes MTA1 and MTA3 are abundantly expressed in human placenta and chorionic carcinoma cells." in: Histochemistry and cell biology, Vol. 132, Issue 1, pp. 33-8, 2009 (PubMed).

Lasky-Su, Neale, Franke et al.: "Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 147B, Issue 8, pp. 1345-54, 2008 (PubMed).

Zhang, Singh, Talukder et al.: "Metastatic tumor antigen 3 is a direct corepressor of the Wnt4 pathway." in: Genes & development, Vol. 20, Issue 21, pp. 2943-8, 2006 (PubMed).

Yu, Hsu, Chen et al.: "Breast cancer risk associated with genotypic polymorphism of the genes involved in the estrogen-receptor-signaling pathway: a multigenic study on cancer susceptibility." in: Journal of biomedical science, Vol. 13, Issue 3, pp. 419-32, 2006 (PubMed).

Fujita, Jaye, Geigerman et al.: "MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation." in: Cell, Vol. 119, Issue 1, pp. 75-86, 2004 (PubMed).

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