Metastasis Associated 1 Family, Member 3 (MTA3) (C-Term), (AA 558-587) antibody

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Antigen
Synonyms MTA3, DKFZp468E247, 1110002J22Rik, mKIAA1266
Epitope
C-Term, AA 558-587
(10), (7), (5), (3), (2), (1), (1)
Reactivity
Human
(30), (4), (4), (1), (1), (1)
Host
Rabbit
(21), (9)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
ELISA, Western Blotting (WB)
(22), (13), (5), (4), (2), (2), (2), (1)
Pubmed 5 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
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Catalog No. ABIN953531
357.50 $
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Immunogen Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 558-587aa) of human MTA3.
Specificity This antibody recognizes human MTA3 at C-term.
Purification Purified through a Protein A column followed by peptide affinity purification
Alternative Name MTA3
Background MTA3 plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels.
Alternate names: KIAA1266, Metastasis-associated protein MTA3
Molecular Weight 67504 Da
Gene ID 57504
NCBI Accession NP_065795
Research Area Cancer, Transcription Factors
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Fujita, Jaye, Geigerman et al.: "MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation." in: Cell, Vol. 119, Issue 1, pp. 75-86, 2004 (PubMed).

Yu, Hsu, Chen et al.: "Breast cancer risk associated with genotypic polymorphism of the genes involved in the estrogen-receptor-signaling pathway: a multigenic study on cancer susceptibility." in: Journal of biomedical science, Vol. 13, Issue 3, pp. 419-32, 2006 (PubMed).

Zhang, Singh, Talukder et al.: "Metastatic tumor antigen 3 is a direct corepressor of the Wnt4 pathway." in: Genes & development, Vol. 20, Issue 21, pp. 2943-8, 2006 (PubMed).

Lasky-Su, Neale, Franke et al.: "Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 147B, Issue 8, pp. 1345-54, 2008 (PubMed).

Brüning, Makovitzky, Gingelmaier et al.: "The metastasis-associated genes MTA1 and MTA3 are abundantly expressed in human placenta and chorionic carcinoma cells." in: Histochemistry and cell biology, Vol. 132, Issue 1, pp. 33-8, 2009 (PubMed).

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